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Morphological components detection for super-depth-of-field bio-micrograph based on deep learning

Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance a...

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Detalles Bibliográficos
Autores principales: Du, Xiaohui, Wang, Xiangzhou, Xu, Fan, Zhang, Jing, Huo, Yibo, Ni, Guangmin, Hao, Ruqian, Liu, Juanxiu, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799896/
https://www.ncbi.nlm.nih.gov/pubmed/34417804
http://dx.doi.org/10.1093/jmicro/dfab033
Descripción
Sumario:Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance an object detection algorithm for cells in the SDoF micrograph based on Retinanet model. Compared with the current mainstream algorithm, the mean average precision (mAP) index is significantly improved. In the experiment of leucorrhea samples and fecal samples, mAP indexes are 83.1% and 88.1%, respectively, with an average increase of 10%. The object detection model proposed in this paper can be applied to feces and leucorrhea detection equipment, and significantly improve the detection efficiency and accuracy.