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Morphological components detection for super-depth-of-field bio-micrograph based on deep learning

Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance a...

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Autores principales: Du, Xiaohui, Wang, Xiangzhou, Xu, Fan, Zhang, Jing, Huo, Yibo, Ni, Guangmin, Hao, Ruqian, Liu, Juanxiu, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799896/
https://www.ncbi.nlm.nih.gov/pubmed/34417804
http://dx.doi.org/10.1093/jmicro/dfab033
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author Du, Xiaohui
Wang, Xiangzhou
Xu, Fan
Zhang, Jing
Huo, Yibo
Ni, Guangmin
Hao, Ruqian
Liu, Juanxiu
Liu, Lin
author_facet Du, Xiaohui
Wang, Xiangzhou
Xu, Fan
Zhang, Jing
Huo, Yibo
Ni, Guangmin
Hao, Ruqian
Liu, Juanxiu
Liu, Lin
author_sort Du, Xiaohui
collection PubMed
description Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance an object detection algorithm for cells in the SDoF micrograph based on Retinanet model. Compared with the current mainstream algorithm, the mean average precision (mAP) index is significantly improved. In the experiment of leucorrhea samples and fecal samples, mAP indexes are 83.1% and 88.1%, respectively, with an average increase of 10%. The object detection model proposed in this paper can be applied to feces and leucorrhea detection equipment, and significantly improve the detection efficiency and accuracy.
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spelling pubmed-87998962022-01-31 Morphological components detection for super-depth-of-field bio-micrograph based on deep learning Du, Xiaohui Wang, Xiangzhou Xu, Fan Zhang, Jing Huo, Yibo Ni, Guangmin Hao, Ruqian Liu, Juanxiu Liu, Lin Microscopy (Oxf) Article Accompanied with the clinical routine examination demand increase sharply, the efficiency and accuracy are the first priority. However, automatic classification and localization of cells in microscopic images in super depth of Field (SDoF) system remains great challenges. In this paper, we advance an object detection algorithm for cells in the SDoF micrograph based on Retinanet model. Compared with the current mainstream algorithm, the mean average precision (mAP) index is significantly improved. In the experiment of leucorrhea samples and fecal samples, mAP indexes are 83.1% and 88.1%, respectively, with an average increase of 10%. The object detection model proposed in this paper can be applied to feces and leucorrhea detection equipment, and significantly improve the detection efficiency and accuracy. Oxford University Press 2021-08-21 /pmc/articles/PMC8799896/ /pubmed/34417804 http://dx.doi.org/10.1093/jmicro/dfab033 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Article
Du, Xiaohui
Wang, Xiangzhou
Xu, Fan
Zhang, Jing
Huo, Yibo
Ni, Guangmin
Hao, Ruqian
Liu, Juanxiu
Liu, Lin
Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title_full Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title_fullStr Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title_full_unstemmed Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title_short Morphological components detection for super-depth-of-field bio-micrograph based on deep learning
title_sort morphological components detection for super-depth-of-field bio-micrograph based on deep learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799896/
https://www.ncbi.nlm.nih.gov/pubmed/34417804
http://dx.doi.org/10.1093/jmicro/dfab033
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