Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity

Enzalutamide, a second-generation antiandrogen, is commonly prescribed for the therapy of advanced prostate cancer, but enzalutamide-resistant, lethal, or incurable disease invariably develops. To understand the molecular mechanism(s) behind enzalutamide resistance, here, we comprehensively analyzed...

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Detalles Bibliográficos
Autores principales: Monga, Jitender, Adrianto, Indra, Rogers, Craig, Gadgeel, Shirish, Chitale, Dhananjay, Alumkal, Joshi J., Beltran, Himisha, Zoubeidi, Amina, Ghosh, Jagadananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800106/
https://www.ncbi.nlm.nih.gov/pubmed/34973338
http://dx.doi.org/10.1016/j.jbc.2021.101556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800106/
https://www.ncbi.nlm.nih.gov/pubmed/34973338
http://dx.doi.org/10.1016/j.jbc.2021.101556

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