SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons

Modulation of the neuronal K(+)/Cl(−) cotransporter 2 (KCC2) activity, which mediates Cl(−) export, is critical to neuronal function. Here, we demonstrate that KCC2 interacts with the SNARE protein synaptosome-associated protein 23, SNAP23, an essential component of membrane insertion machinery. Usi...

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Detalles Bibliográficos
Autores principales: Asraf, Hila, Bogdanovic, Milos, Gottesman, Noa, Sekler, Israel, Aizenman, Elias, Hershfinkel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800107/
https://www.ncbi.nlm.nih.gov/pubmed/35118363
http://dx.doi.org/10.1016/j.isci.2022.103751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800107/
https://www.ncbi.nlm.nih.gov/pubmed/35118363
http://dx.doi.org/10.1016/j.isci.2022.103751

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