Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina

The breakdown of all-trans-retinal (atRAL) clearance is closely associated with photoreceptor cell death in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt's disease (STGD1), but its mechanisms remain elusive. Here, we demonstrate that activation of gasdermin E (GSD...

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Detalles Bibliográficos
Autores principales: Cai, Binxiang, Liao, Chunyan, He, Danxue, Chen, Jingmeng, Han, Jiahuai, Lu, Jiaying, Qin, Kaiqi, Liang, Wenxu, Wu, Xiaoling, Liu, Zuguo, Wu, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800116/
https://www.ncbi.nlm.nih.gov/pubmed/34973334
http://dx.doi.org/10.1016/j.jbc.2021.101553

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