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Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19
The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co-infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800164/ https://www.ncbi.nlm.nih.gov/pubmed/35127454 http://dx.doi.org/10.1016/j.idcr.2022.e01428 |
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author | Tzar, Mohd Nizam Meor Jamaludin, Wan Husna Barakah Abdul Wahab, Asrul Ding, Chuan Hun |
author_facet | Tzar, Mohd Nizam Meor Jamaludin, Wan Husna Barakah Abdul Wahab, Asrul Ding, Chuan Hun |
author_sort | Tzar, Mohd Nizam |
collection | PubMed |
description | The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co-infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed. |
format | Online Article Text |
id | pubmed-8800164 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88001642022-01-31 Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 Tzar, Mohd Nizam Meor Jamaludin, Wan Husna Barakah Abdul Wahab, Asrul Ding, Chuan Hun IDCases Case Report The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co-infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed. Elsevier 2022-01-29 /pmc/articles/PMC8800164/ /pubmed/35127454 http://dx.doi.org/10.1016/j.idcr.2022.e01428 Text en © 2022 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Tzar, Mohd Nizam Meor Jamaludin, Wan Husna Barakah Abdul Wahab, Asrul Ding, Chuan Hun Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title | Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title_full | Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title_fullStr | Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title_full_unstemmed | Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title_short | Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19 |
title_sort | exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with covid-19 |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800164/ https://www.ncbi.nlm.nih.gov/pubmed/35127454 http://dx.doi.org/10.1016/j.idcr.2022.e01428 |
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