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Serum hepatitis B virus RNA detectability, composition and clinical significance in patients with ab initio hepatitis B e antigen negative chronic hepatitis B

BACKGROUND: Serum hepatitis B virus (HBV) RNA is a surrogate biomarker for intrahepatic covalently closed circular DNA (cccDNA) transcriptional activity and persistence. In this retrospective study, we investigated its presence, levels and composition in ab initio Hepatitis B e antigen (HBeAg) negat...

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Detalles Bibliográficos
Autores principales: Laras, Andreas, Papatheodoridi, Margarita, Panopoulou, Eleni, Papatheodoridis, George V., Hadziyannis, Stephanos J., Hadziyannis, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800272/
https://www.ncbi.nlm.nih.gov/pubmed/35093105
http://dx.doi.org/10.1186/s12985-022-01749-7