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Epithelial microRNA-30a-3p targets RUNX2/HMGB1 axis to suppress airway eosinophilic inflammation in asthma

BACKGROUND: Type 2-high asthma is a prominent endotype of asthma which is characterized by airway eosinophilic inflammation. Airway epithelial cells play a critical role in the pathogenesis of asthma. Our previous miRNA profiling data showed that miR-30a-3p was downregulated in bronchial epithelial...

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Detalles Bibliográficos
Autores principales:	Wu, Wenliang, Gao, Jiali, Chen, Dian, Chen, Gongqi, Feng, Yuchen, Chang, Chenli, Chen, Shengchong, Yi, Lingling, Zhen, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800331/ https://www.ncbi.nlm.nih.gov/pubmed/35093061 http://dx.doi.org/10.1186/s12931-022-01933-x

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