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AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800413/ https://www.ncbi.nlm.nih.gov/pubmed/35125607 http://dx.doi.org/10.1007/s10462-021-10109-w |
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author | Zhang, Zhan Jiao, Yang Zhang, Mingxia Wei, Bing Liu, Xiao Zhao, Juan Tian, Fengwei Hu, Jie Zhang, Qin |
author_facet | Zhang, Zhan Jiao, Yang Zhang, Mingxia Wei, Bing Liu, Xiao Zhao, Juan Tian, Fengwei Hu, Jie Zhang, Qin |
author_sort | Zhang, Zhan |
collection | PubMed |
description | Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have these problems. This paper extends DUCG to include the representation and inference algorithm for non-causal classification relationships. As a part of general clinical diagnoses, six knowledge bases corresponding to six chief complaints (arthralgia, dyspnea, cough and expectoration, epistaxis, fever with rash and abdominal pain) were constructed through constructing subgraphs relevant to a chief complaint separately and synthesizing them together as the knowledge base of the chief complaint. A subgraph represents variables and causalities related to a single disease that may cause the chief complaint, regardless of which hospital department the disease belongs to. Verified by two groups of third-party hospitals independently, total diagnostic precisions of the six knowledge bases ranged in 96.5–100%, in which the precision for every disease was no less than 80%. |
format | Online Article Text |
id | pubmed-8800413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-88004132022-01-31 AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification Zhang, Zhan Jiao, Yang Zhang, Mingxia Wei, Bing Liu, Xiao Zhao, Juan Tian, Fengwei Hu, Jie Zhang, Qin Artif Intell Rev Article Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have these problems. This paper extends DUCG to include the representation and inference algorithm for non-causal classification relationships. As a part of general clinical diagnoses, six knowledge bases corresponding to six chief complaints (arthralgia, dyspnea, cough and expectoration, epistaxis, fever with rash and abdominal pain) were constructed through constructing subgraphs relevant to a chief complaint separately and synthesizing them together as the knowledge base of the chief complaint. A subgraph represents variables and causalities related to a single disease that may cause the chief complaint, regardless of which hospital department the disease belongs to. Verified by two groups of third-party hospitals independently, total diagnostic precisions of the six knowledge bases ranged in 96.5–100%, in which the precision for every disease was no less than 80%. Springer Netherlands 2022-01-29 2022 /pmc/articles/PMC8800413/ /pubmed/35125607 http://dx.doi.org/10.1007/s10462-021-10109-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Zhang, Zhan Jiao, Yang Zhang, Mingxia Wei, Bing Liu, Xiao Zhao, Juan Tian, Fengwei Hu, Jie Zhang, Qin AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title | AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title_full | AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title_fullStr | AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title_full_unstemmed | AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title_short | AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
title_sort | ai-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800413/ https://www.ncbi.nlm.nih.gov/pubmed/35125607 http://dx.doi.org/10.1007/s10462-021-10109-w |
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