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AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification

Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have...

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Detalles Bibliográficos
Autores principales: Zhang, Zhan, Jiao, Yang, Zhang, Mingxia, Wei, Bing, Liu, Xiao, Zhao, Juan, Tian, Fengwei, Hu, Jie, Zhang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800413/
https://www.ncbi.nlm.nih.gov/pubmed/35125607
http://dx.doi.org/10.1007/s10462-021-10109-w
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author Zhang, Zhan
Jiao, Yang
Zhang, Mingxia
Wei, Bing
Liu, Xiao
Zhao, Juan
Tian, Fengwei
Hu, Jie
Zhang, Qin
author_facet Zhang, Zhan
Jiao, Yang
Zhang, Mingxia
Wei, Bing
Liu, Xiao
Zhao, Juan
Tian, Fengwei
Hu, Jie
Zhang, Qin
author_sort Zhang, Zhan
collection PubMed
description Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have these problems. This paper extends DUCG to include the representation and inference algorithm for non-causal classification relationships. As a part of general clinical diagnoses, six knowledge bases corresponding to six chief complaints (arthralgia, dyspnea, cough and expectoration, epistaxis, fever with rash and abdominal pain) were constructed through constructing subgraphs relevant to a chief complaint separately and synthesizing them together as the knowledge base of the chief complaint. A subgraph represents variables and causalities related to a single disease that may cause the chief complaint, regardless of which hospital department the disease belongs to. Verified by two groups of third-party hospitals independently, total diagnostic precisions of the six knowledge bases ranged in 96.5–100%, in which the precision for every disease was no less than 80%.
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spelling pubmed-88004132022-01-31 AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification Zhang, Zhan Jiao, Yang Zhang, Mingxia Wei, Bing Liu, Xiao Zhao, Juan Tian, Fengwei Hu, Jie Zhang, Qin Artif Intell Rev Article Artificial intelligence (AI)-aided general clinical diagnosis is helpful to primary clinicians. Machine learning approaches have problems of generalization, interpretability, etc. Dynamic Uncertain Causality Graph (DUCG) based on uncertain casual knowledge provided by clinical experts does not have these problems. This paper extends DUCG to include the representation and inference algorithm for non-causal classification relationships. As a part of general clinical diagnoses, six knowledge bases corresponding to six chief complaints (arthralgia, dyspnea, cough and expectoration, epistaxis, fever with rash and abdominal pain) were constructed through constructing subgraphs relevant to a chief complaint separately and synthesizing them together as the knowledge base of the chief complaint. A subgraph represents variables and causalities related to a single disease that may cause the chief complaint, regardless of which hospital department the disease belongs to. Verified by two groups of third-party hospitals independently, total diagnostic precisions of the six knowledge bases ranged in 96.5–100%, in which the precision for every disease was no less than 80%. Springer Netherlands 2022-01-29 2022 /pmc/articles/PMC8800413/ /pubmed/35125607 http://dx.doi.org/10.1007/s10462-021-10109-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhang, Zhan
Jiao, Yang
Zhang, Mingxia
Wei, Bing
Liu, Xiao
Zhao, Juan
Tian, Fengwei
Hu, Jie
Zhang, Qin
AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title_full AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title_fullStr AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title_full_unstemmed AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title_short AI-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
title_sort ai-aided general clinical diagnoses verified by third-parties with dynamic uncertain causality graph extended to also include classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800413/
https://www.ncbi.nlm.nih.gov/pubmed/35125607
http://dx.doi.org/10.1007/s10462-021-10109-w
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