Cargando…

The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling

Bromodomain-containing protein 7 (BRD7) has been shown to interact with the regulatory subunit of phosphatidylinositol 3-kinase (PI3K), p85, in the insulin signaling pathway. Here, we show that upregulation of hepatic BRD7 improves glucose homeostasis even in the absence of either p85 isoform, p85α...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Junsik M, Liu, Renyan, Park, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800525/
https://www.ncbi.nlm.nih.gov/pubmed/34751372
http://dx.doi.org/10.1093/jmcb/mjab073

Ejemplares similares