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An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review

Flavonoids are present naturally in many fruits and vegetables including onions, apples, tea, cabbage, cauliflower, berries and nuts which provide us with quercetin, a powerful natural antioxidant and cytotoxic compound. Due to antioxidant property, many nutraceuticals and cosmeceuticals products co...

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Autores principales: Azeem, Muhammad, Hanif, Muhammad, Mahmood, Khalid, Ameer, Nabeela, Chughtai, Fazal Rahman Sajid, Abid, Usman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800825/
https://www.ncbi.nlm.nih.gov/pubmed/35125574
http://dx.doi.org/10.1007/s00289-022-04091-8
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author Azeem, Muhammad
Hanif, Muhammad
Mahmood, Khalid
Ameer, Nabeela
Chughtai, Fazal Rahman Sajid
Abid, Usman
author_facet Azeem, Muhammad
Hanif, Muhammad
Mahmood, Khalid
Ameer, Nabeela
Chughtai, Fazal Rahman Sajid
Abid, Usman
author_sort Azeem, Muhammad
collection PubMed
description Flavonoids are present naturally in many fruits and vegetables including onions, apples, tea, cabbage, cauliflower, berries and nuts which provide us with quercetin, a powerful natural antioxidant and cytotoxic compound. Due to antioxidant property, many nutraceuticals and cosmeceuticals products contain quercetin as a major ingredient nowadays. Current review enlightened sources and quercetin’s role as an antioxidant, antimicrobial, antidiabetic, anticancerous and anti-inflammatory agent in medical field during last 5 to 6 years. Literature search was systematically done using scientific for the published articles of quercetin. A total of 345 articles were reviewed, and it was observed that more than 40% of articles were about quercetin’s use as an antioxidant agent, more than 25% of studies were about its use as an anticancer agent, and articles on antimicrobial activity were more than 15%. 10% of the articles showed anti-inflamamatory effects of quercetin. Literature search also revealed that quercetin alone and its complexes with chitosan, metal ions and polymers possessed good antidiabetic properties. Thus, the review focuses on new therapeutic interventions and drug delivery system of quercetin in medical field for the benefit of mankind.
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spelling pubmed-88008252022-01-31 An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review Azeem, Muhammad Hanif, Muhammad Mahmood, Khalid Ameer, Nabeela Chughtai, Fazal Rahman Sajid Abid, Usman Polym Bull (Berl) Review Paper Flavonoids are present naturally in many fruits and vegetables including onions, apples, tea, cabbage, cauliflower, berries and nuts which provide us with quercetin, a powerful natural antioxidant and cytotoxic compound. Due to antioxidant property, many nutraceuticals and cosmeceuticals products contain quercetin as a major ingredient nowadays. Current review enlightened sources and quercetin’s role as an antioxidant, antimicrobial, antidiabetic, anticancerous and anti-inflammatory agent in medical field during last 5 to 6 years. Literature search was systematically done using scientific for the published articles of quercetin. A total of 345 articles were reviewed, and it was observed that more than 40% of articles were about quercetin’s use as an antioxidant agent, more than 25% of studies were about its use as an anticancer agent, and articles on antimicrobial activity were more than 15%. 10% of the articles showed anti-inflamamatory effects of quercetin. Literature search also revealed that quercetin alone and its complexes with chitosan, metal ions and polymers possessed good antidiabetic properties. Thus, the review focuses on new therapeutic interventions and drug delivery system of quercetin in medical field for the benefit of mankind. Springer Berlin Heidelberg 2022-01-30 2023 /pmc/articles/PMC8800825/ /pubmed/35125574 http://dx.doi.org/10.1007/s00289-022-04091-8 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Paper
Azeem, Muhammad
Hanif, Muhammad
Mahmood, Khalid
Ameer, Nabeela
Chughtai, Fazal Rahman Sajid
Abid, Usman
An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title_full An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title_fullStr An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title_full_unstemmed An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title_short An insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
title_sort insight into anticancer, antioxidant, antimicrobial, antidiabetic and anti-inflammatory effects of quercetin: a review
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800825/
https://www.ncbi.nlm.nih.gov/pubmed/35125574
http://dx.doi.org/10.1007/s00289-022-04091-8
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