Cargando…

Neoantigens and the tumor microenvironment play important roles in the prognosis of high-grade serous ovarian cancer

BACKGROUND: Despite the consistency of patient age, disease stage and treatment options, the prognosis of different high-grade serous ovarian carcinoma (HGSOC) patients is different. Here, we sought to measure predictive biomarkers for distinct responses to platinum-based chemotherapy and immunother...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hua, Yu, Mei, Zhong, Sen, You, Yan, Feng, Fengzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801100/ https://www.ncbi.nlm.nih.gov/pubmed/35093146 http://dx.doi.org/10.1186/s13048-022-00955-9

Ejemplares similares

Deciphering tumor immune microenvironment differences between high-grade serous and endometrioid ovarian cancer to investigate their potential in indicating immunotherapy response
por: Yang, Hua, et al.
Publicado: (2023)

The Tumor Microenvironment of High Grade Serous Ovarian Cancer
por: Stack, M. Sharon, et al.
Publicado: (2018)

Th2 cells infiltrating high-grade serous ovarian cancer: a feature that may account for the poor prognosis
por: Su, Hao, et al.
Publicado: (2023)

Targeting the Microenvironment in High Grade Serous Ovarian Cancer
por: Nwani, Nkechiyere G., et al.
Publicado: (2018)

The peritoneal tumour microenvironment of high-grade serous ovarian cancer
por: Leinster, D Andrew, et al.
Publicado: (2012)

Ovarian low and high grade serous carcinomas: hidden divergent features in the tumor microenvironment
por: Ciucci, Alessandra, et al.
Publicado: (2016)

Dynamics of the Tumor Immune Microenvironment during Neoadjuvant Chemotherapy of High-Grade Serous Ovarian Cancer
por: Lee, Yong Jae, et al.
Publicado: (2022)

Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma
por: Matsushita, Hirokazu, et al.
Publicado: (2020)

Single-Cell RNA-Sequencing Atlas Reveals the Tumor Microenvironment of Metastatic High-Grade Serous Ovarian Carcinoma
por: Deng, Yingqing, et al.
Publicado: (2022)

Testing for NRAS Mutations in Serous Borderline Ovarian Tumors and Low-Grade Serous Ovarian Carcinomas
por: Sadlecki, Pawel, et al.
Publicado: (2018)

PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome
por: Salvi, Amrita, et al.
Publicado: (2022)

Model constructions of chemosensitivity and prognosis of high grade serous ovarian cancer based on evaluation of immune microenvironment and immune response
por: Zhang, Han, et al.
Publicado: (2021)

Tumor and local lymphoid tissue interaction determines prognosis in high-grade serous ovarian cancer
por: Lu, Haonan, et al.
Publicado: (2023)

High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
por: Gonzalez, Veronica D., et al.
Publicado: (2021)

Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer
por: Launonen, I.-M., et al.
Publicado: (2022)

Exploiting Autophagy-Dependent Neoantigen Presentation in Tumor Microenvironment
por: Koustas, Evangelos, et al.
Publicado: (2023)

Dynamically Accumulating Homologous Recombination Deficiency Score Served as an Important Prognosis Factor in High-Grade Serous Ovarian Cancer
por: Su, Rongjia, et al.
Publicado: (2021)

Overview of Tumor Heterogeneity in High-Grade Serous Ovarian Cancers
por: Azzalini, Eros, et al.
Publicado: (2023)

Proteomic Discovery of Biomarkers to Predict Prognosis of High-Grade Serous Ovarian Carcinoma
por: Kim, Se Ik, et al.
Publicado: (2020)

AKT Isoforms Interplay in High-Grade Serous Ovarian Cancer Prognosis and Characterization
por: Azzalini, Eros, et al.
Publicado: (2022)

Identification of Prognosis Biomarkers for High-Grade Serous Ovarian Cancer Based on Stemness
por: Wang, Zhihang, et al.
Publicado: (2022)

Low-grade Serous Ovarian Carcinoma
por: Ricciardi, Enzo, et al.
Publicado: (2018)

Tumor core biopsies adequately represent immune microenvironment of high-grade serous carcinoma
por: Lara, Olivia D., et al.
Publicado: (2019)

The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma
por: Shen, Yuanming, et al.
Publicado: (2022)

Nadir CA-125 level as prognosis indicator of high-grade serous ovarian cancer
por: Xu, Xia, et al.
Publicado: (2013)

Abnormal methylation characteristics predict chemoresistance and poor prognosis in advanced high-grade serous ovarian cancer
por: Feng, Li-yuan, et al.
Publicado: (2021)

Development of Low-Grade Serous Ovarian Carcinoma from Benign Ovarian Serous Cystadenoma Cells
por: Dey, Puja, et al.
Publicado: (2022)

Age is associated with prognosis in serous ovarian carcinoma
por: Deng, Fei, et al.
Publicado: (2017)

The prognostic significance of tumor-immune microenvironment in ascites of patients with high-grade serous carcinoma
por: Miceska, Simona, et al.
Publicado: (2023)

Tumor Mutation Burden, Expressed Neoantigens and the Immune Microenvironment in Diffuse Gliomas
por: Yu, Guangyang, et al.
Publicado: (2021)

Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer
por: Heindl, Andreas, et al.
Publicado: (2016)

CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
por: Yang, Moran, et al.
Publicado: (2021)

High expression of CD8 in the tumor microenvironment is associated with PD-1 expression and patient survival in high-grade serous ovarian cancer
por: Ölmez, Fatma, et al.
Publicado: (2022)

VISTA expression is associated with a favorable prognosis in patients with high-grade serous ovarian cancer
por: Zong, Liju, et al.
Publicado: (2019)

Low Expression of RGS2 Promotes Poor Prognosis in High-Grade Serous Ovarian Cancer
por: Ihlow, Jana, et al.
Publicado: (2022)

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer
por: Strickland, Kyle C., et al.
Publicado: (2016)

Prognostic significance of intra-tumoral budding in high-grade serous ovarian carcinomas
por: Hachisuga, Toru, et al.
Publicado: (2022)

Classification of High-Grade Serous Ovarian Cancer Using Tumor Morphologic Characteristics
por: Handley, Katelyn F., et al.
Publicado: (2022)

MRI for differentiating ovarian endometrioid adenocarcinoma from high-grade serous adenocarcinoma
por: Li, Hai Ming, et al.
Publicado: (2015)

Tumour microenvironment‐based molecular profiling reveals ideal candidates for high‐grade serous ovarian cancer immunotherapy
por: Lu, Xiaofan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_c43op5ernc1vmgt5jhp6vdv3bn