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Integrating RNA-Seq With GWAS Reveals a Novel SNP in Immune-Related HLA-DQB1 Gene Associated With Occupational Pulmonary Fibrosis Risk: A Multi-Stage Study

OBJECTIVE: To evaluate the association between single-nucleotide polymorphisms (SNPs) in RNA-seq identified mRNAs and silicosis susceptibility. METHODS: A comprehensive RNA-seq was performed to screen for differently expressed mRNAs in the peripheral blood lymphocytes of eight subjects exposed to si...

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Detalles Bibliográficos
Autores principales:	Zhou, Yan, Zhang, Yingyi, Zhao, Rui, Cheng, Zhounan, Tang, Minzhu, Qiu, Anni, Dong, Yang, Lu, Yihua, Lian, Yulong, Zhuang, Xun, Tian, Tian, Wang, Wei, Chu, Minjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801455/ https://www.ncbi.nlm.nih.gov/pubmed/35111164 http://dx.doi.org/10.3389/fimmu.2021.796932

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