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PRMT5 Inhibition Promotes PD-L1 Expression and Immuno-Resistance in Lung Cancer

Protein arginine transferase 5 (PRMT5) has been implicated as an important modulator of tumorigenesis as it promotes tumor cell proliferation, invasion, and metastasis. Studies have largely focused on PRMT5 regulating intrinsic changes in tumors; however, the effects of PRMT5 on the tumor microenvir...

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Detalles Bibliográficos
Autores principales: Hu, Rui, Zhou, Bingqian, Chen, Zheyi, Chen, Shiyu, Chen, Ningdai, Shen, Lisong, Xiao, Haibo, Zheng, Yingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801487/
https://www.ncbi.nlm.nih.gov/pubmed/35111150
http://dx.doi.org/10.3389/fimmu.2021.722188