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PRMT5 Inhibition Promotes PD-L1 Expression and Immuno-Resistance in Lung Cancer
Protein arginine transferase 5 (PRMT5) has been implicated as an important modulator of tumorigenesis as it promotes tumor cell proliferation, invasion, and metastasis. Studies have largely focused on PRMT5 regulating intrinsic changes in tumors; however, the effects of PRMT5 on the tumor microenvir...
Autores principales: | Hu, Rui, Zhou, Bingqian, Chen, Zheyi, Chen, Shiyu, Chen, Ningdai, Shen, Lisong, Xiao, Haibo, Zheng, Yingxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801487/ https://www.ncbi.nlm.nih.gov/pubmed/35111150 http://dx.doi.org/10.3389/fimmu.2021.722188 |
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