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Activated Platelets Autocrine 5-Hydroxytryptophan Aggravates Sepsis-Induced Acute Lung Injury by Promoting Neutrophils Extracellular Traps Formation

Excessive neutrophil extracellular trap (NET) formation is an important contributor to sepsis-induced acute lung injury (ALI). Recent reports indicate that platelets can induce neutrophil extracellular trap formation. However, the specific mechanism remains unclear. Tph1 gene, which encodes the rate...

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Detalles Bibliográficos
Autores principales: Huang, Yumeng, Ji, Qian, Zhu, Yanyan, Fu, Shengqiao, Chen, Shuangwei, Chu, Liangmei, Ren, Yongfei, Wang, Yue, Lei, Xuan, Gu, Jia, Tai, Ningzheng, Liu, Dadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801939/
https://www.ncbi.nlm.nih.gov/pubmed/35111753
http://dx.doi.org/10.3389/fcell.2021.777989