Cargando…

Combination of ultra-purified stem cells with an in situ-forming bioresorbable gel enhances intervertebral disc regeneration

BACKGROUND: Lumbar intervertebral disc (IVD) herniations are associated with significant disability. Discectomy is the conventional treatment option for IVD herniations but causes a defect in the IVD, which has low self-repair ability, thereby representing a risk of further IVD degeneration. An acel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ukeba, Daisuke, Yamada, Katsuhisa, Suyama, Takashi, Lebl, Darren R., Tsujimoto, Takeru, Nonoyama, Takayuki, Sugino, Hirokazu, Iwasaki, Norimasa, Watanabe, Masatoki, Matsuzaki, Yumi, Sudo, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801983/ https://www.ncbi.nlm.nih.gov/pubmed/35085848 http://dx.doi.org/10.1016/j.ebiom.2022.103845

Ejemplares similares

An acellular bioresorbable ultra-purified alginate gel promotes intervertebral disc repair: A preclinical proof-of-concept study
por: Tsujimoto, Takeru, et al.
Publicado: (2018)

Ultra-purified alginate gel implantation decreases inflammatory cytokine levels, prevents intervertebral disc degeneration, and reduces acute pain after discectomy
por: Ura, Katsuro, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs
por: Ukeba, Daisuke, et al.
Publicado: (2020)

Injection of Ultra-Purified Stem Cells with Sodium Alginate Reduces Discogenic Pain in a Rat Model
por: Suzuki, Hisataka, et al.
Publicado: (2023)

A Review: Methodologies to Promote the Differentiation of Mesenchymal Stem Cells for the Regeneration of Intervertebral Disc Cells Following Intervertebral Disc Degeneration
por: Ohnishi, Takashi, et al.
Publicado: (2023)

Effects of Single Injection of Local Anesthetic Agents on Intervertebral Disc Degeneration: Ex Vivo and Long-Term In Vivo Experimental Study
por: Iwasaki, Koji, et al.
Publicado: (2014)

Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging
por: Ohnishi, Takashi, et al.
Publicado: (2019)

In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification
por: Ohnishi, Takashi, et al.
Publicado: (2016)

Biomaterials and Cell-Based Regenerative Therapies for Intervertebral Disc Degeneration with a Focus on Biological and Biomechanical Functional Repair: Targeting Treatments for Disc Herniation
por: Yamada, Katsuhisa, et al.
Publicado: (2022)

Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model
por: Sudo, Hideki, et al.
Publicado: (2013)

Causes of and Molecular Targets for the Treatment of Intervertebral Disc Degeneration: A Review
por: Ohnishi, Takashi, et al.
Publicado: (2022)

Cytotoxic Effects of the Radiocontrast Agent Iotrolan and Anesthetic Agents Bupivacaine and Lidocaine in Three-Dimensional Cultures of Human Intervertebral Disc Nucleus Pulposus Cells: Identification of the Apoptotic Pathways
por: Iwasaki, Koji, et al.
Publicado: (2014)

Evaluation of Surgical Indications for Full Endoscopic Discectomy at Lumbosacral Disc Levels Using Three-Dimensional Magnetic Resonance/Computed Tomography Fusion Images Created with Artificial Intelligence
por: Yamada, Katsuhisa, et al.
Publicado: (2023)

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
por: Sano, Tomohiko, et al.
Publicado: (2019)

Quantitative Assessment of Intervertebral Disc Composition by MRI: Sensitivity to Diurnal Variation
por: Hamaguchi, Hiroyuki, et al.
Publicado: (2023)

Influence of Lateral Translation of Lowest Instrumented Vertebra on L4 Tilt and Coronal Balance for Thoracolumbar and Lumbar Curves in Adolescent Idiopathic Scoliosis
por: Yamada, Katsuhisa, et al.
Publicado: (2023)

Gel and cells: A promising reparative strategy for degenerated intervertebral discs
por: Tuan, Rocky S.
Publicado: (2020)

RANK/RANKL/OPG system in the intervertebral disc
por: Takegami, Norihiko, et al.
Publicado: (2017)

Perioperative Complications of Open Spine Surgery in Older Adults over 90 Years of Age
por: Tsujimoto, Takeru, et al.
Publicado: (2022)

The intervertebral disc /
por: De Palma, Anthony F.
Publicado: (1970)

Expression of Glial-Cell-Line-Derived Neurotrophic Factor Family Ligands in Human Intervertebral Discs
por: Iwasaki, Tatsuya, et al.
Publicado: (2023)

Prediction of Cobb Angle Using Deep Learning Algorithm with Three-Dimensional Depth Sensor Considering the Influence of Garment in Idiopathic Scoliosis
por: Ishikawa, Yoko, et al.
Publicado: (2023)

Intervertebral disc disease in Dachshunds radiographically screened for intervertebral disc calcifications
por: Lappalainen, Anu K, et al.
Publicado: (2014)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Mechanotransduction in intervertebral discs
por: Tsai, Tsung-Ting, et al.
Publicado: (2014)

Prolapsed Intervertebral Disc
por: Alexander, G. L., et al.
Publicado: (1947)

The Intervertebral Disc and Sciatica
Publicado: (1945)

Development of Notch-Free, Pre-Bent Rod Applicable for Posterior Corrective Surgery of Thoracolumbar/Lumbar Adolescent Idiopathic Scoliosis
por: Ishikawa, Yoko, et al.
Publicado: (2023)

Intradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model
por: Sudo, Takao, et al.
Publicado: (2021)

Intervertebral disc cell- and hydrogel-supported and spontaneous intervertebral disc repair in nucleotomized sheep
por: Benz, Karin, et al.
Publicado: (2012)

Genetic and Functional Studies of the Intervertebral Disc: A Novel Murine Intervertebral Disc Model
por: Pelle, Dominic W., et al.
Publicado: (2014)

Intervertebral Disc Stem/Progenitor Cells: A Promising “Seed” for Intervertebral Disc Regeneration
por: Du, Yuxiang, et al.
Publicado: (2021)

An Injectable Engineered Cartilage Gel Improves Intervertebral Disc Repair in a Rat Nucleotomy Model
por: Bhujel, Basanta, et al.
Publicado: (2023)

The Role of IL-17-Mediated Inflammatory Processes in the Pathogenesis of Intervertebral Disc Degeneration and Herniation: A Comprehensive Review
por: Suyama, Kaori, et al.
Publicado: (2022)

The Development and Growth of the Intervertebral Disc
por: Walmsley, Robert
Publicado: (1953)

Classification of Intervertebral Disc Disease
por: Fenn, Joe, et al.
Publicado: (2020)

Imaging diagnosis for intervertebral disc
por: Ogon, Izaya, et al.
Publicado: (2019)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3mvdf8034deeho6actectmv2ls