m6A-dependent upregulation of TRAF6 by METTL3 is associated with metastatic osteosarcoma

OBJECTIVES: RNA N6-methyladenosine (m6A) is associated with tumorigenesis. The importance of methyltransferase-like 3 (METTL3) has been reported in cancer progression and metastasis. However, its role and molecular mechanism in osteosarcoma (OS), the most common primary bone tumor, is poorly studied...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Wang, Wentao, Huang, Xing, Cao, Jiashi, Hou, Shuming, Ni, Xiangzhi, Peng, Cheng, Liu, Tielong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802048/
https://www.ncbi.nlm.nih.gov/pubmed/35145841
http://dx.doi.org/10.1016/j.jbo.2022.100411

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