Cargando…

Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats

Numerous studies indicate a significant role for cytochrome P-450-dependent arachidonic acid metabolites in blood pressure regulation, vascular tone, and control of renal function. Epoxyeicosatrienoic acids (EETs) exhibit a spectrum of beneficial effects, such as vasodilatory activity and anti-infla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baranowska, Iwona, Gawrys, Olga, Walkowska, Agnieszka, Olszynski, Krzysztof H., Červenka, Luděk, Falck, John R., Adebesin, Adeniyi M., Imig, John D., Kompanowska-Jezierska, Elżbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802114/ https://www.ncbi.nlm.nih.gov/pubmed/35111064 http://dx.doi.org/10.3389/fphar.2021.798642

Ejemplares similares

Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats
por: Walkowska, Agnieszka, et al.
Publicado: (2021)

Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation
por: Kala, Petr, et al.
Publicado: (2021)

High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity
por: Walkowska, A., et al.
Publicado: (2015)

Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury
por: Hye Khan, Md. Abdul, et al.
Publicado: (2014)

Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity
por: Imig, John D., et al.
Publicado: (2021)

Chymase Dependent Pathway of Angiotensin II Generation and Rapeseed Derived Peptides for Antihypertensive Treatment of Spontaneously Hypertensive Rats
por: Baranowska, Iwona, et al.
Publicado: (2021)

Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions
por: Imig, John D., et al.
Publicado: (2010)

Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure
por: Vacková, Šárka, et al.
Publicado: (2019)

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats
por: Sedláková, Lenka, et al.
Publicado: (2018)

Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension
por: Kala, Petr, et al.
Publicado: (2023)

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats
por: Kujal, Petr, et al.
Publicado: (2014)

Kidney Response to Chemotherapy-Induced Heart Failure: mRNA Analysis in Normotensive and Ren-2 Transgenic Hypertensive Rats
por: Jíchová, Šárka, et al.
Publicado: (2021)

Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats
por: Neckář, Jan, et al.
Publicado: (2019)

Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice
por: Hye Khan, Md. Abdul, et al.
Publicado: (2019)

Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats
por: Hrdlička, Jaroslav, et al.
Publicado: (2019)

Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
por: Vacková, Šárka, et al.
Publicado: (2019)

Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition
por: Skibba, Melissa, et al.
Publicado: (2017)

Polyprenol-Based Lipofecting Agents for In Vivo Delivery of Therapeutic DNA to Treat Hypertensive Rats
por: Gawrys, Olga, et al.
Publicado: (2020)

Impaired renal autoregulation and pressure-natriuresis: any role in the development of heart failure in normotensive and angiotensin II-dependent hypertensive rats?
por: Honetschlägerová, Zuzana, et al.
Publicado: (2023)

Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats
por: Chábová, Věra Čertíková, et al.
Publicado: (2019)

Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat
por: Kala, Petr, et al.
Publicado: (2020)

Erratum on: Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury
Publicado: (2014)

Nonselective and A2a-Selective Inhibition of Adenosine Receptors Modulates Renal Perfusion and Excretion Depending on the Duration of Streptozotocin-Induced Diabetes in Rats
por: Sitek, Joanna Dorota, et al.
Publicado: (2023)

Conflicting Roles of 20-HETE in Hypertension and Stroke
por: Shekhar, Shashank, et al.
Publicado: (2019)

Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ET(A) Blockade
por: Vaněčková, Ivana, et al.
Publicado: (2019)

Afferent arteriolar responses to β,γ-methylene ATP and 20-HETE are not blocked by ENaC inhibition
por: Nagasawa, Tasuku, et al.
Publicado: (2013)

The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula
por: Gawrys, Olga, et al.
Publicado: (2023)

20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis
por: Han, Ranran, et al.
Publicado: (2021)

Androgen-sensitive hypertension associated with soluble guanylate cyclase alpha1 deficiency is mediated by 20-HETE
por: Vandenwijngaert, Sara, et al.
Publicado: (2015)

Effect of Chronically Suppressed Plasma Angiotensin II on Regulation of the CYP4A/20-HETE Pathway in the Dahl Salt-Sensitive Rat
por: Lukaszewicz, Kathleen, et al.
Publicado: (2023)

Peroxisome proliferator-activated receptors, farnesoid X receptor, and dual modulating drugs in hypertension
por: Imig, John D.
Publicado: (2023)

Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes
por: Kim, Dong Hyun, et al.
Publicado: (2013)

Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids
por: Thomson, Scott J., et al.
Publicado: (2012)

The role of epoxyeicosatrienoic acids in the cardiovascular system
por: Yang, L, et al.
Publicado: (2015)

Inside epoxyeicosatrienoic acids and cardiovascular disease
por: Tacconelli, Stefania, et al.
Publicado: (2014)

The Role of Epoxyeicosatrienoic Acids in Cardiac Remodeling
por: Lai, Jinsheng, et al.
Publicado: (2021)

Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response
por: Samokhvalov, V, et al.
Publicado: (2013)

A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3–NLRP3 Pathway
por: Darwesh, Ahmed M., et al.
Publicado: (2020)

Aging, Estrogen Loss and Epoxyeicosatrienoic Acids (EETs)
por: Lee, Alison R., et al.
Publicado: (2013)

Regio- and Enantioselective Catalytic Monoepoxidation of Conjugated Dienes: Synthesis of Chiral Allylic cis-Epoxides
por: Jat, Jawahar L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_glqnks247f7id0qitjc0a79qc8