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Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model
Excessive interleukin (IL)-6 production is a driver for malignancy and drug resistance in colorectal cancer (CRC). Our study investigated a seven-week post-treatment with the anti-inflammatory drug, Diacerein (Diac), alone or in combination with 5-fluorouracil (5-FU), using a 1,2-dimethylhydrazine (...
Autores principales: | Abdel-Latif, Raghda T., Wadie, Walaa, Abdel-mottaleb, Yousra, Abdallah, Dalaal M., El-Maraghy, Nabila N., El-Abhar, Hanan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802128/ https://www.ncbi.nlm.nih.gov/pubmed/35145347 http://dx.doi.org/10.1016/j.jsps.2021.12.009 |
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