Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells

Emerging evidence has shown that the therapy-induced senescent growth arrest in cancer cells is of durable nature whereby a subset of cells can reinstate proliferative capacity. Promising new drugs named senolytics selectively target senescent cells and commit them into apoptosis. Accordingly, senol...

Descripción completa

Detalles Bibliográficos
Autores principales: As Sobeai, Homood M., Alohaydib, Munirah, Alhoshani, Ali R., Alhazzani, Khalid, Almutairi, Mashal M., Saleh, Tareq, Gewirtz, David A., Alotiabi, Moureq R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802130/
https://www.ncbi.nlm.nih.gov/pubmed/35145348
http://dx.doi.org/10.1016/j.jsps.2021.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802130/
https://www.ncbi.nlm.nih.gov/pubmed/35145348
http://dx.doi.org/10.1016/j.jsps.2021.12.004

Ejemplares similares