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Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells

Emerging evidence has shown that the therapy-induced senescent growth arrest in cancer cells is of durable nature whereby a subset of cells can reinstate proliferative capacity. Promising new drugs named senolytics selectively target senescent cells and commit them into apoptosis. Accordingly, senol...

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Detalles Bibliográficos
Autores principales:	As Sobeai, Homood M., Alohaydib, Munirah, Alhoshani, Ali R., Alhazzani, Khalid, Almutairi, Mashal M., Saleh, Tareq, Gewirtz, David A., Alotiabi, Moureq R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802130/ https://www.ncbi.nlm.nih.gov/pubmed/35145348 http://dx.doi.org/10.1016/j.jsps.2021.12.004

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