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Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients

Human B cells and their expressed antibodies are crucial in conferring immune protection. Identifying pathogen-specific antibodies following infection is possible due to enhanced humoral immunity against well-described molecules on the pathogen surface. However, screening for cancer-reactive antibod...

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Detalles Bibliográficos
Autores principales: Karagiannis, Panagiotis, Correa, Isabel, Chauhan, Jitesh, Cheung, Anthony, Dominguez-Rodriguez, Diana, Terranova-Barberio, Manuela, Harris, Robert J, Crescioli, Silvia, Spicer, James, Bokemeyer, Carsten, Lacy, Katie E, Karagiannis, Sophia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802180/
https://www.ncbi.nlm.nih.gov/pubmed/35020866
http://dx.doi.org/10.1093/cei/uxab005