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ApoA-I mimetics favorably impact cyclooxygenase 2 and bioactive lipids that may contribute to cardiometabolic syndrome in chronic treated HIV
OBJECTIVE: We investigated whether apolipoprotein A-I (apoA-I) mimetic peptides 4F and 6F can be a novel therapeutic strategy to reduce blood and gut bioactive lipids, proinflammatory effects of endotoxin (LPS) and aberrant activation of cyclooxygenase 2 (COX-2) as instigators of increased risk for...
Autores principales: | Daskou, M., Sharma, M., Mu, W., Heymans, R., Ritou, E., Rezek, V., Hamid, P., Kossyvakis, A., Sen Roy, S., Grijalva, V., Chattopadhyay, A., Papesh, J., Meriwether, D., Kitchen, S.G., Fogelman, A.M., Reddy, S.T., Kelesidis, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802211/ https://www.ncbi.nlm.nih.gov/pubmed/34509494 http://dx.doi.org/10.1016/j.metabol.2021.154888 |
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