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Lung adenocarcinoma-specific three-integrin signature contributes to poor outcomes by metastasis and immune escape pathways

BACKGROUND: Inhibitors targeting integrins (ITGs) are applied as a novel strategy for cancers including lung cancer; however, the heterogeneity of ITG subunits might explain why ITG-targeted inhibitors only show limited efficacy for a small group of lung cancer patients. MATERIALS AND METHODS: RNA-S...

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Detalles Bibliográficos
Autores principales: Wang, Yizhe, Hou, Kezuo, Jin, Yue, Bao, Bowen, Tang, Shiying, Qi, Jianfei, Yang, Yang, Che, Xiaofang, Liu, Yunpeng, Hu, Xuejun, Zheng, Chunlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802404/
https://www.ncbi.nlm.nih.gov/pubmed/35136724
http://dx.doi.org/10.2478/jtim-2021-0046