Cargando…

Lung adenocarcinoma-specific three-integrin signature contributes to poor outcomes by metastasis and immune escape pathways

BACKGROUND: Inhibitors targeting integrins (ITGs) are applied as a novel strategy for cancers including lung cancer; however, the heterogeneity of ITG subunits might explain why ITG-targeted inhibitors only show limited efficacy for a small group of lung cancer patients. MATERIALS AND METHODS: RNA-S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yizhe, Hou, Kezuo, Jin, Yue, Bao, Bowen, Tang, Shiying, Qi, Jianfei, Yang, Yang, Che, Xiaofang, Liu, Yunpeng, Hu, Xuejun, Zheng, Chunlei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802404/ https://www.ncbi.nlm.nih.gov/pubmed/35136724 http://dx.doi.org/10.2478/jtim-2021-0046

Ejemplares similares

Identification of Prognostic Signature and Gliclazide as Candidate Drugs in Lung Adenocarcinoma
por: Cheng, Yang, et al.
Publicado: (2021)

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
por: Yan, Hongfei, et al.
Publicado: (2019)

Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib-resistant non-small cell lung cancer cells
por: Yang, Yang, et al.
Publicado: (2021)

Bioinformatics-Based Identification of HDAC Inhibitors as Potential Drugs to Target EGFR Wild-Type Non-Small-Cell Lung Cancer
por: Wang, Yizhe, et al.
Publicado: (2021)

LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2021)

Correction to: LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/ miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2021)

Correction: LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/ miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2023)

N(6)-Methyladenosine RNA Demethylase FTO Promotes Gastric Cancer Metastasis by Down-Regulating the m6A Methylation of ITGB1
por: Wang, Duo, et al.
Publicado: (2021)

Reduced Expression of METTL3 Promotes Metastasis of Triple-Negative Breast Cancer by m6A Methylation-Mediated COL3A1 Up-Regulation
por: Shi, Yu, et al.
Publicado: (2020)

miR-1323 Promotes Cell Migration in Lung Adenocarcinoma by Targeting Cbl-b and Is an Early Prognostic Biomarker
por: Zhao, Huan, et al.
Publicado: (2020)

Identification of Subtype-Specific Three-Gene Signature for Prognostic Prediction in Diffuse Type Gastric Cancer
por: Bao, Bowen, et al.
Publicado: (2019)

Knockdown of G‐protein‐signaling modulator 2 promotes metastasis of non‐small‐cell lung cancer by inducing the expression of Snail
por: Deng, Mingming, et al.
Publicado: (2020)

Comparative Analysis and in vitro Experiments of Signatures and Prognostic Value of Immune Checkpoint Genes in Colorectal Cancer
por: Ma, Rui, et al.
Publicado: (2021)

M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer
por: Cao, Lili, et al.
Publicado: (2019)

Localization of GPSM2 in the Nucleus of Invasive Breast Cancer Cells Indicates a Poor Prognosis
por: Deng, Mingming, et al.
Publicado: (2020)

Succinylation Regulators Promote Clear Cell Renal Cell Carcinoma by Immune Regulation and RNA N6-Methyladenosine Methylation
por: Lu, Wenqing, et al.
Publicado: (2021)

Distinct prognostic values of programmed death-ligand 1 and programmed cell death protein 1 in lung adenocarcinoma and squamous cell carcinoma patients
por: Wang, Shuo, et al.
Publicado: (2021)

Assessment of Nine Driver Gene Mutations in Surgically Resected Samples from Patients with Non-Small-Cell Lung Cancer
por: Wang, Shuo, et al.
Publicado: (2020)

CircHIPK3 Promotes Metastasis of Gastric Cancer via miR-653-5p/miR-338-3p-NRP1 Axis Under a Long-Term Hypoxic Microenvironment
por: Jin, Yue, et al.
Publicado: (2020)

Corrigendum: CircHIPK3 Promotes Metastasis of Gastric Cancer via miR-653-5p/miR-338-3p-NRP1 Axis Under a Long-Term Hypoxic Microenvironment
por: Jin, Yue, et al.
Publicado: (2021)

Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex
por: Fang, Wanxia, et al.
Publicado: (2020)

Correction to: Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex
por: Fang, Wanxia, et al.
Publicado: (2021)

Hypoxia-autophagy axis induces VEGFA by peritoneal mesothelial cells to promote gastric cancer peritoneal metastasis through an integrin α5-fibronectin pathway
por: Wang, Xiaoxun, et al.
Publicado: (2020)

Elevated limb-bud and heart development (LBH) expression indicates poor prognosis and promotes gastric cancer cell proliferation and invasion via upregulating Integrin/FAK/Akt pathway
por: Yu, Ruoxi, et al.
Publicado: (2019)

DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53-deficient pancreatic cancer cells
por: Jing, Wei, et al.
Publicado: (2018)

microRNA-569 inhibits tumor metastasis in pancreatic cancer by directly targeting NUSAP1
por: Guo, Xiaohui, et al.
Publicado: (2022)

E3 Ubiquitin Ligase Cbl-b Prevents Tumor Metastasis by Maintaining the Epithelial Phenotype in Multiple Drug-Resistant Gastric and Breast Cancer Cells()
por: Xu, Ling, et al.
Publicado: (2017)

Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors
por: ZHAO, LEI, et al.
Publicado: (2015)

MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma
por: Li, Ce, et al.
Publicado: (2018)

Down-regulation of interleukin-2 predicts poor prognosis and associated with immune escape in lung adenocarcinoma
por: Hou, Yongwang, et al.
Publicado: (2023)

The immune escape signature predicts the prognosis and immunotherapy sensitivity for pancreatic ductal adenocarcinoma
por: Lu, Hao, et al.
Publicado: (2022)

Identification of Key Gene and Pathways for the Prediction of Peritoneal Metastasis of Gastric Cancer by Co-expression Analysis
por: Zhang, Simeng, et al.
Publicado: (2020)

A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells
por: Song, Na, et al.
Publicado: (2017)

GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of α2M
por: Liu, Chang, et al.
Publicado: (2020)

Genome-Wide Identification of a Novel Eight-lncRNA Signature to Improve Prognostic Prediction in Head and Neck Squamous Cell Carcinoma
por: Yang, Bowen, et al.
Publicado: (2019)

Identification of Ferroptosis-Related Genes Signature Predicting the Efficiency of Invasion and Metastasis Ability in Colon Adenocarcinoma
por: Shi, Chunlei, et al.
Publicado: (2022)

Hypoxia-induced ALDH3A1 promotes the proliferation of non-small-cell lung cancer by regulating energy metabolism reprogramming
por: Chen, Yang, et al.
Publicado: (2023)

Construction of disulfidptosis-related lncRNA signature for predicting the prognosis and immune escape in colon adenocarcinoma
por: Chen, Pan, et al.
Publicado: (2023)

GPR115 Contributes to Lung Adenocarcinoma Metastasis Associated With LAMC2 and Predicts a Poor Prognosis
por: Wang, Yingjing, et al.
Publicado: (2020)

Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells
por: Gong, Jing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_trvcc5g6rcqp1k5nauf5brolq6