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Building and breaking the gut barrier with bariatric surgery
Bariatric surgery has been proposed to improve glycemic control in morbidly obese patients by stabilising the gut barrier and alleviating endotoxemia-induced insulin resistance. Here, recent studies are highlighted which reveal site-specific and at times opposing effects of bariatric surgery on the...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Shared Science Publishers OG
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802433/ https://www.ncbi.nlm.nih.gov/pubmed/35174316 http://dx.doi.org/10.15698/cst2022.02.263 |
| _version_ | 1784642668722126848 |
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| author | Hankir, Mohammed K. |
| author_facet | Hankir, Mohammed K. |
| author_sort | Hankir, Mohammed K. |
| collection | PubMed |
| description | Bariatric surgery has been proposed to improve glycemic control in morbidly obese patients by stabilising the gut barrier and alleviating endotoxemia-induced insulin resistance. Here, recent studies are highlighted which reveal site-specific and at times opposing effects of bariatric surgery on the gut barrier. Further understanding the underlying mechanisms may not only inform the development of novel gut-based drugs for the initial treatment of type 2 diabetes, but possibly also assist in the management of its eventual relapse. |
| format | Online Article Text |
| id | pubmed-8802433 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Shared Science Publishers OG |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-88024332022-02-15 Building and breaking the gut barrier with bariatric surgery Hankir, Mohammed K. Cell Stress News and Thoughts Bariatric surgery has been proposed to improve glycemic control in morbidly obese patients by stabilising the gut barrier and alleviating endotoxemia-induced insulin resistance. Here, recent studies are highlighted which reveal site-specific and at times opposing effects of bariatric surgery on the gut barrier. Further understanding the underlying mechanisms may not only inform the development of novel gut-based drugs for the initial treatment of type 2 diabetes, but possibly also assist in the management of its eventual relapse. Shared Science Publishers OG 2021-12-22 /pmc/articles/PMC8802433/ /pubmed/35174316 http://dx.doi.org/10.15698/cst2022.02.263 Text en Copyright: © 2021 Hankir https://creativecommons.org/licenses/by/4.0/This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged. |
| spellingShingle | News and Thoughts Hankir, Mohammed K. Building and breaking the gut barrier with bariatric surgery |
| title | Building and breaking the gut barrier with bariatric surgery |
| title_full | Building and breaking the gut barrier with bariatric surgery |
| title_fullStr | Building and breaking the gut barrier with bariatric surgery |
| title_full_unstemmed | Building and breaking the gut barrier with bariatric surgery |
| title_short | Building and breaking the gut barrier with bariatric surgery |
| title_sort | building and breaking the gut barrier with bariatric surgery |
| topic | News and Thoughts |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802433/ https://www.ncbi.nlm.nih.gov/pubmed/35174316 http://dx.doi.org/10.15698/cst2022.02.263 |
| work_keys_str_mv | AT hankirmohammedk buildingandbreakingthegutbarrierwithbariatricsurgery |