TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α degradation

BACKGROUND: Tumor cell metabolic reprogramming is crucial for the malignant behavior of cancer cells by promoting their proliferation. However, little is known on how transient receptor potential 7 (TRPM7) modulates metabolic reprogramming in ovarian cancer. METHODS: The effects of TRPM7 silencing o...

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Detalles Bibliográficos
Autores principales: Chen, Yongchang, Liu, Lu, Xia, Longzheng, Wu, Nayiyuan, Wang, Ying, Li, He, Chen, Xue, Zhang, Xiaoye, Liu, Zhaoyi, Zhu, Miaochen, Liao, Qianjin, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802454/
https://www.ncbi.nlm.nih.gov/pubmed/35101076
http://dx.doi.org/10.1186/s13046-022-02252-1

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