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Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)

INTRODUCTION: The importance of balloon aortic valvuloplasty (BAV) in the transcatheter aortic valve implantation (TAVI) era emerged in the past decades, but the access site related complication rate remained significant. AIM: To establish the safety and technical success of transradial balloon aort...

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Autores principales: Molnár, Levente, Papp, Roland, Szigethi, Tímea, Édes, István F., Becker, Dávid, Bertrand, Olivier F., Merkely, Béla, Ruzsa, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802645/
https://www.ncbi.nlm.nih.gov/pubmed/35126553
http://dx.doi.org/10.5114/aic.2021.111341
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author Molnár, Levente
Papp, Roland
Szigethi, Tímea
Édes, István F.
Becker, Dávid
Bertrand, Olivier F.
Merkely, Béla
Ruzsa, Zoltán
author_facet Molnár, Levente
Papp, Roland
Szigethi, Tímea
Édes, István F.
Becker, Dávid
Bertrand, Olivier F.
Merkely, Béla
Ruzsa, Zoltán
author_sort Molnár, Levente
collection PubMed
description INTRODUCTION: The importance of balloon aortic valvuloplasty (BAV) in the transcatheter aortic valve implantation (TAVI) era emerged in the past decades, but the access site related complication rate remained significant. AIM: To establish the safety and technical success of transradial balloon aortic valvuloplasty (trBAV). The secondary objective was to determine the effectiveness and appropriate role of trBAV. MATERIAL AND METHODS: Between 2017 and 2019, 36 consecutive patients with symptomatic aortic stenosis (AoS) were treated with trBAV in this prospective, single-center study. During the procedure, the efficacy and the aortic valve insufficiency were controlled by hemodynamic measurements and later by echocardiography. The primary end-points were technical success and major adverse events (MAE). Secondary end-points were the access site complication rate, hemodynamic and clinical result of the intervention, procedure-related factors, crossover rate to the femoral access site and hospitalization duration. RESULTS: Clinical and technical success was achieved in all cases. Invasively measured peak-to-peak gradient decreased from 76.8 ±27.2 to 54.7 ±21.1 mm Hg (p = 0.001), and the aortic-valve area increased from 0.69 ±0.2 to 0.91 ±0.3 cm(2) (p = 0.001). No major adverse cardiac or cerebrovascular events or vascular complications (according to VARC 2 criteria) occurred during the procedures. The perioperative death rate was 2.7% (n = 1). CONCLUSIONS: According to our study, radial artery access is a safe and effective option for balloon aortic valvuloplasty in patients with severe aortic valve stenosis.
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spelling pubmed-88026452022-02-04 Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study) Molnár, Levente Papp, Roland Szigethi, Tímea Édes, István F. Becker, Dávid Bertrand, Olivier F. Merkely, Béla Ruzsa, Zoltán Postepy Kardiol Interwencyjnej Original Paper INTRODUCTION: The importance of balloon aortic valvuloplasty (BAV) in the transcatheter aortic valve implantation (TAVI) era emerged in the past decades, but the access site related complication rate remained significant. AIM: To establish the safety and technical success of transradial balloon aortic valvuloplasty (trBAV). The secondary objective was to determine the effectiveness and appropriate role of trBAV. MATERIAL AND METHODS: Between 2017 and 2019, 36 consecutive patients with symptomatic aortic stenosis (AoS) were treated with trBAV in this prospective, single-center study. During the procedure, the efficacy and the aortic valve insufficiency were controlled by hemodynamic measurements and later by echocardiography. The primary end-points were technical success and major adverse events (MAE). Secondary end-points were the access site complication rate, hemodynamic and clinical result of the intervention, procedure-related factors, crossover rate to the femoral access site and hospitalization duration. RESULTS: Clinical and technical success was achieved in all cases. Invasively measured peak-to-peak gradient decreased from 76.8 ±27.2 to 54.7 ±21.1 mm Hg (p = 0.001), and the aortic-valve area increased from 0.69 ±0.2 to 0.91 ±0.3 cm(2) (p = 0.001). No major adverse cardiac or cerebrovascular events or vascular complications (according to VARC 2 criteria) occurred during the procedures. The perioperative death rate was 2.7% (n = 1). CONCLUSIONS: According to our study, radial artery access is a safe and effective option for balloon aortic valvuloplasty in patients with severe aortic valve stenosis. Termedia Publishing House 2021-12-30 2021-12 /pmc/articles/PMC8802645/ /pubmed/35126553 http://dx.doi.org/10.5114/aic.2021.111341 Text en Copyright: © 2021 Termedia Sp. z o. o. https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Molnár, Levente
Papp, Roland
Szigethi, Tímea
Édes, István F.
Becker, Dávid
Bertrand, Olivier F.
Merkely, Béla
Ruzsa, Zoltán
Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title_full Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title_fullStr Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title_full_unstemmed Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title_short Safety and feasibility of transradial aortic valve valvuloplasty (TRAV study)
title_sort safety and feasibility of transradial aortic valve valvuloplasty (trav study)
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802645/
https://www.ncbi.nlm.nih.gov/pubmed/35126553
http://dx.doi.org/10.5114/aic.2021.111341
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