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Structural identification and absolute quantification of monoclonal antibodies in suspected counterfeits using capillary electrophoresis and liquid chromatography-tandem mass spectrometry

Monoclonal antibodies (mAbs) represent a major category of biopharmaceutical products which due to their success as therapeutics have recently experienced the emergence of mAbs originating from different types of trafficking. We report the development of an analytical strategy which enables the stru...

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Detalles Bibliográficos
Autores principales: Legrand, Pauline, Dembele, Oumar, Alamil, Héléna, Lamoureux, Catherine, Mignet, Nathalie, Houzé, Pascal, Gahoual, Rabah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802745/
https://www.ncbi.nlm.nih.gov/pubmed/35099584
http://dx.doi.org/10.1007/s00216-022-03913-y