Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment

Galectin-3 (Gal3) can be expressed by many cells in the tumor microenvironment (TME), including cancer cells, cancer-associated fibroblasts, tumor-associated macrophages, and regulatory T cells (Tregs). In addition to immunosuppression, Gal3 expression has been connected to malignant cell transforma...

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Detalles Bibliográficos
Autores principales: Bendtsen, Simone Kloch, Perez-Penco, Maria, Hübbe, Mie Linder, Martinenaite, Evelina, Orebo Holmström, Morten, Weis-Banke, Stine Emilie, Grønne Dahlager Jørgensen, Nicolai, Jørgensen, Mia Aaboe, Munir Ahmad, Shamaila, Jensen, Kasper Mølgaard, Friese, Christina, Lundsager, Mia Thorup, Johansen, Astrid Zedlitz, Carretta, Marco, Ødum, Niels, Met, Özcan, Svane, Inge Marie, Madsen, Daniel Hargbøl, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802901/
https://www.ncbi.nlm.nih.gov/pubmed/35111385
http://dx.doi.org/10.1080/2162402X.2022.2026020

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