Cargando…

Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis

AIMS : Fibroblast growth factor (FGF) 21, a key regulator of energy metabolism, is currently evaluated in humans for treatment of type 2 diabetes and non-alcoholic steatohepatitis. However, the effects of FGF21 on cardiovascular benefit, particularly on lipoprotein metabolism in relation to atheroge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Cong, Schönke, Milena, Zhou, Enchen, Li, Zhuang, Kooijman, Sander, Boon, Mariëtte R, Larsson, Mikael, Wallenius, Kristina, Dekker, Niek, Barlind, Louise, Peng, Xiao-Rong, Wang, Yanan, Rensen, Patrick C N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803070/ https://www.ncbi.nlm.nih.gov/pubmed/33693480 http://dx.doi.org/10.1093/cvr/cvab076

Ejemplares similares

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis
por: Liu, Cong, et al.
Publicado: (2023)

Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans
por: Ying, Zhixiong, et al.
Publicado: (2022)

Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice
por: Bartesaghi, Stefano, et al.
Publicado: (2022)

Mild Exercise Does Not Prevent Atherosclerosis in APOE*3‐Leiden.CETP Mice or Improve Lipoprotein Profile of Men with Obesity
por: In het Panhuis, Wietse, et al.
Publicado: (2020)

Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development
por: Zhou, Enchen, et al.
Publicado: (2020)

A simplified procedure to trace triglyceride‐rich lipoprotein metabolism in vivo
por: Ying, Zhixiong, et al.
Publicado: (2021)

Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice
por: van Eenige, Robin, et al.
Publicado: (2021)

Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice
por: Kooijman, Sander, et al.
Publicado: (2015)

Therapeutic FGF19 promotes HDL biogenesis and transhepatic cholesterol efflux to prevent atherosclerosis
por: Zhou, Mei, et al.
Publicado: (2019)

Electrical Neurostimulation Promotes Brown Adipose Tissue Thermogenesis
por: Li, Zhuang, et al.
Publicado: (2020)

Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice
por: In Het Panhuis, Wietse, et al.
Publicado: (2023)

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions
por: Thiem, Kathrin, et al.
Publicado: (2019)

Aging attenuates diurnal lipid uptake by brown adipose tissue
por: In het Panhuis, Wietse, et al.
Publicado: (2022)

Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice
por: Schilperoort, Maaike, et al.
Publicado: (2020)

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
por: Berbée, Jimmy F. P., et al.
Publicado: (2015)

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice
por: Hoekstra, Menno, et al.
Publicado: (2021)

Cholesterol: Enhancing FGF2 translocation in unconventional secretion
por: Wang, Haodong, et al.
Publicado: (2022)

Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals
por: van den Berg, Rosa, et al.
Publicado: (2016)

Free Cholesterol Bioavailability and Atherosclerosis
por: Abe, Rei J., et al.
Publicado: (2022)

Strong association of glaucoma with atherosclerosis
por: Song, Xianqin, et al.
Publicado: (2021)

Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice
por: Ying, Zhixiong, et al.
Publicado: (2023)

The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue
por: Sardjoe Mishre, Aashley S. D., et al.
Publicado: (2022)

Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4
por: Li, Zhuang, et al.
Publicado: (2023)

Modulation of foraging-like behaviors by cholesterol-FGF19 axis
por: Huang, Alyssa, et al.
Publicado: (2023)

THE EFFECT OF ALLOXAN DIABETES ON EXPERIMENTAL CHOLESTEROL ATHEROSCLEROSIS IN THE RABBIT : I. THE INHIBITION OF EXPERIMENTAL CHOLESTEROL ATHEROSCLEROSIS IN ALLOXAN DIABETES II. THE EFFECT OF ALLOXAN DIABETES ON THE RETROGRESSION OF EXPERIMENTAL CHOLESTEROL ATHEROSCLEROSIS
por: Duff, G. Lyman, et al.
Publicado: (1949)

Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs
por: Koopmans, Sietse J, et al.
Publicado: (2011)

Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice
por: Zhao, Jungang, et al.
Publicado: (2021)

THE EFFECT OF UNDERNUTRITION ON CHOLESTEROL ATHEROSCLEROSIS IN THE RABBIT
por: McMillan, Gardner C., et al.
Publicado: (1954)

Macrophage‐mediated cholesterol handling in atherosclerosis
por: Chistiakov, Dimitry A., et al.
Publicado: (2015)

Cholesterol efflux pathways, inflammation, and atherosclerosis
por: Groenen, Anouk G., et al.
Publicado: (2021)

Contribution of Remnant Cholesterol to Coronary Atherosclerosis
por: Ohmura, Hirotoshi
Publicado: (2022)

Computationally Modelling Cholesterol Metabolism and Atherosclerosis
por: Davies, Callum, et al.
Publicado: (2023)

T-cell Cholesterol Accumulation, Aging, and Atherosclerosis
por: Bazioti, Venetia, et al.
Publicado: (2023)

Effect of Dietary Cholesterol and Cholesterol Oxides on Blood Cholesterol, Lipids, and the Development of Atherosclerosis in Rabbits
por: Hur, Sun Jin, et al.
Publicado: (2013)

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
por: Bartelt, Alexander, et al.
Publicado: (2017)

Can aerobic exercise really be a ‘warm‐up’ for brown adipose tissue?
por: Schönke, Milena, et al.
Publicado: (2022)

A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding
por: Paalvast, Yared, et al.
Publicado: (2022)

Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease
por: Kovynev, Artemiy, et al.
Publicado: (2023)

THE RELATION BETWEEN ATHEROSCLEROSIS AND INGESTED CHOLESTEROL IN THE RABBIT
por: Clarkson, Sarah, et al.
Publicado: (1926)

Cholesterol; is accused for the atherosclerosis proximal to myocardial bridging?
por: Aparcı, Mustafa, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_smkrfic63vm5icvo8s2iig61ao