Safety, mucosal and systemic immunopotency of an aerosolized adenovirus-vectored vaccine against SARS-CoV-2 in rhesus macaques

Mucosal immunity provides a potential for preventing initial infection and stopping subsequent transmission of SARS-CoV-2. Here, we examined the safety and immunogenicity of a replication-defective adenovirus type-5 vectored vaccine (Ad5-nCov) encoding SARS-CoV-2 spike protein delivered by nebulizat...

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Detalles Bibliográficos
Autores principales: Xu, Fang, Wu, Shipo, Yi, Linan, Peng, Shaodan, Wang, Fan, Si, Weixue, Hou, Lihua, Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803102/
https://www.ncbi.nlm.nih.gov/pubmed/35094672
http://dx.doi.org/10.1080/22221751.2022.2030199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803102/
https://www.ncbi.nlm.nih.gov/pubmed/35094672
http://dx.doi.org/10.1080/22221751.2022.2030199

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