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S1P/S1PR3 signalling axis protects against obesity-induced metabolic dysfunction

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that interacts via 5 G-protein coupled receptors, S1PR1-5, to regulate signalling pathways critical to biological processes including cell growth, immune cell trafficking, and inflammation.We demonstrate that in Type 2 diabetic (T2D) subjects...

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Detalles Bibliográficos
Autores principales: Chakrabarty, Sagarika, Bui, Quyen, Badeanlou, Leylla, Hester, Kelly, Chun, Jerold, Ruf, Wolfram, Ciaraldi, Theodore P, Samad, Fahumiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803104/
https://www.ncbi.nlm.nih.gov/pubmed/35094654
http://dx.doi.org/10.1080/21623945.2021.2021700