Structural and functional characterization of a monoclonal antibody blocking TIGIT

TIGIT is an immune checkpoint receptor that is expressed on subsets of activated T cells and natural killer (NK) cells. Several ligands for TIGIT, including poliovirus receptor (PVR), are expressed on cancer cells and mediate inhibitory signaling to suppress antitumor activities of the immune cells....

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Detalles Bibliográficos
Autores principales: Jeong, Bo-Seong, Nam, Hyemi, Lee, Jeewon, Park, Hye-Young, Cho, Ki Joon, Sheen, Joong Hyuk, Song, Eunjung, Oh, Meesook, Lee, Sunggeun, Choi, Hyemin, Yang, Jung-Eun, Kim, Munkyung, Oh, Byung-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803117/
https://www.ncbi.nlm.nih.gov/pubmed/35090381
http://dx.doi.org/10.1080/19420862.2021.2013750

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