Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes

Malignant cell transformation and the underlying reprogramming of gene expression require the cooperation of multiple oncogenic mutations. This cooperation is reflected in the synergistic regulation of non-mutant downstream genes, so-called cooperation response genes (CRGs). CRGs affect diverse hall...

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Detalles Bibliográficos
Autores principales: McMurray, Helene R., Ambeskovic, Aslihan, Newman, Laurel A., Aldersley, Jordan, Balakrishnan, Vijaya, Smith, Bradley, Stern, Harry A., Land, Hartmut, McCall, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803128/
https://www.ncbi.nlm.nih.gov/pubmed/34936873
http://dx.doi.org/10.1016/j.celrep.2021.110136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803128/
https://www.ncbi.nlm.nih.gov/pubmed/34936873
http://dx.doi.org/10.1016/j.celrep.2021.110136

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