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Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial

BACKGROUND: Insufficient milk production is a common problem affecting breastfeeding women, in particular following Cesarean delivery. Wang Nam Yen herbal tea is a promising traditional Thai medicine used by postpartum women to stimulate milk production, as an alternative to pharmaceutical galactago...

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Autores principales: Saejueng, Koollachart, Nopsopon, Tanawin, Wuttikonsammakit, Piyawadee, Khumbun, Wattanaporn, Pongpirul, Krit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803155/
https://www.ncbi.nlm.nih.gov/pubmed/35100251
http://dx.doi.org/10.1371/journal.pone.0247637
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author Saejueng, Koollachart
Nopsopon, Tanawin
Wuttikonsammakit, Piyawadee
Khumbun, Wattanaporn
Pongpirul, Krit
author_facet Saejueng, Koollachart
Nopsopon, Tanawin
Wuttikonsammakit, Piyawadee
Khumbun, Wattanaporn
Pongpirul, Krit
author_sort Saejueng, Koollachart
collection PubMed
description BACKGROUND: Insufficient milk production is a common problem affecting breastfeeding women, in particular following Cesarean delivery. Wang Nam Yen herbal tea is a promising traditional Thai medicine used by postpartum women to stimulate milk production, as an alternative to pharmaceutical galactagogues. We aimed to compare the efficacy of Wang Nam Yen herbal tea, domperidone, and placebo, in increasing milk production in mothers who underwent Cesarean delivery. METHODS: Women who underwent uncomplicated cesarean delivery at Sunpasitthiprasong Hospital were randomized into three groups. The participants received the treatments daily for three consecutive days. The primary outcome was breast milk volume at 72 hours after delivery. Secondary outcomes were pregnancy and neonatal outcomes, adverse events, and participant satisfaction. RESULTS: Of the 1,450 pregnant women that underwent cesarean delivery, 120 women were enrolled. Their mean age and gestational ages were 28.7 years and 38.4 weeks, respectively. Breast milk volume at 72 hours postpartum was significantly different among the three groups (p = 0.030). The post hoc Bonferroni correction indicated a significant difference in breast milk volume between Wang Nam Yen herbal tea group and placebo control group (p = 0.007) while there was no difference between Wang Nam Yen herbal tea group and domperidone group (p = 0.806) and between domperidone group and placebo control group (p = 0.018). There was no difference in pregnancy and neonatal outcomes, adverse events, and participant satisfaction among the three groups. CONCLUSION: Wang Nam Yen herbal tea was effective in augmenting breast milk production at 72 hours postpartum in mothers following cesarean delivery, and there was no evidence that herbal tea and domperidone differed in terms of augmenting breast milk production. TRIAL REGISTRATION: The study was approved by the institutional review board of Sunpasitthiprasong Hospital (No.061/2559) and was registered TCTR20170811003 with the Thai Clinical Trial Registry.
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spelling pubmed-88031552022-02-01 Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial Saejueng, Koollachart Nopsopon, Tanawin Wuttikonsammakit, Piyawadee Khumbun, Wattanaporn Pongpirul, Krit PLoS One Research Article BACKGROUND: Insufficient milk production is a common problem affecting breastfeeding women, in particular following Cesarean delivery. Wang Nam Yen herbal tea is a promising traditional Thai medicine used by postpartum women to stimulate milk production, as an alternative to pharmaceutical galactagogues. We aimed to compare the efficacy of Wang Nam Yen herbal tea, domperidone, and placebo, in increasing milk production in mothers who underwent Cesarean delivery. METHODS: Women who underwent uncomplicated cesarean delivery at Sunpasitthiprasong Hospital were randomized into three groups. The participants received the treatments daily for three consecutive days. The primary outcome was breast milk volume at 72 hours after delivery. Secondary outcomes were pregnancy and neonatal outcomes, adverse events, and participant satisfaction. RESULTS: Of the 1,450 pregnant women that underwent cesarean delivery, 120 women were enrolled. Their mean age and gestational ages were 28.7 years and 38.4 weeks, respectively. Breast milk volume at 72 hours postpartum was significantly different among the three groups (p = 0.030). The post hoc Bonferroni correction indicated a significant difference in breast milk volume between Wang Nam Yen herbal tea group and placebo control group (p = 0.007) while there was no difference between Wang Nam Yen herbal tea group and domperidone group (p = 0.806) and between domperidone group and placebo control group (p = 0.018). There was no difference in pregnancy and neonatal outcomes, adverse events, and participant satisfaction among the three groups. CONCLUSION: Wang Nam Yen herbal tea was effective in augmenting breast milk production at 72 hours postpartum in mothers following cesarean delivery, and there was no evidence that herbal tea and domperidone differed in terms of augmenting breast milk production. TRIAL REGISTRATION: The study was approved by the institutional review board of Sunpasitthiprasong Hospital (No.061/2559) and was registered TCTR20170811003 with the Thai Clinical Trial Registry. Public Library of Science 2022-01-31 /pmc/articles/PMC8803155/ /pubmed/35100251 http://dx.doi.org/10.1371/journal.pone.0247637 Text en © 2022 Saejueng et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Saejueng, Koollachart
Nopsopon, Tanawin
Wuttikonsammakit, Piyawadee
Khumbun, Wattanaporn
Pongpirul, Krit
Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title_full Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title_fullStr Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title_full_unstemmed Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title_short Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial
title_sort efficacy of wang nam yen herbal tea on human milk production: a randomized controlled trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803155/
https://www.ncbi.nlm.nih.gov/pubmed/35100251
http://dx.doi.org/10.1371/journal.pone.0247637
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