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Extended ensemble simulations of a SARS-CoV-2 nsp1–5’-UTR complex

Nonstructural protein 1 (nsp1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a 180-residue protein that blocks translation of host mRNAs in SARS-CoV-2-infected cells. Although it is known that SARS-CoV-2’s own RNA evades nsp1’s host translation shutoff, the molecular mechanism u...

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Detalles Bibliográficos
Autores principales:	Sakuraba, Shun, Xie, Qilin, Kasahara, Kota, Iwakiri, Junichi, Kono, Hidetoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803185/ https://www.ncbi.nlm.nih.gov/pubmed/35045069 http://dx.doi.org/10.1371/journal.pcbi.1009804

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