Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum

Agouti-related peptide (AgRP) neurons increase motivation for food, however, whether metabolic sensing of homeostatic state in AgRP neurons potentiates motivation by interacting with dopamine reward systems is unexplored. As a model of impaired metabolic-sensing, we used the AgRP-specific deletion o...

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Detalles Bibliográficos
Autores principales: Reichenbach, Alex, Clarke, Rachel E, Stark, Romana, Lockie, Sarah Haas, Mequinion, Mathieu, Dempsey, Harry, Rawlinson, Sasha, Reed, Felicia, Sepehrizadeh, Tara, DeVeer, Michael, Munder, Astrid C, Nunez-Iglesias, Juan, Spanswick, David C, Mynatt, Randall, Kravitz, Alexxai V, Dayas, Christopher V, Brown, Robyn, Andrews, Zane B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803314/
https://www.ncbi.nlm.nih.gov/pubmed/35018884
http://dx.doi.org/10.7554/eLife.72668

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