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Macrophage global metabolomics identifies cholestenone as host/pathogen cometabolite present in human Mycobacterium tuberculosis infection

Mycobacterium tuberculosis (M. tuberculosis) causes an enormous burden of disease worldwide. As a central aspect of its pathogenesis, M. tuberculosis grows in macrophages, and host and microbe influence each other’s metabolism. To define the metabolic impact of M. tuberculosis infection, we performe...

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Detalles Bibliográficos
Autores principales:	Chandra, Pallavi, Coullon, Héloise, Agarwal, Mansi, Goss, Charles W., Philips, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803325/ https://www.ncbi.nlm.nih.gov/pubmed/35104812 http://dx.doi.org/10.1172/JCI152509

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