Cargando…
Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment
Previous studies have shown that treatment with recombinant adropin, a circulating peptide secreted by the liver and brain, restores glucose utilization in the hearts of diet-induced obese mice. This restoration of fuel substrate flexibility, which is lost in obese and diabetic animals, has the pote...
Autores principales: | Thapa, Dharendra, Xie, Bingxian, Mushala, Bellina A.S., Zhang, Manling, Manning, Janet R., Bugga, Paramesha, Stoner, Michael W., Jurczak, Michael J., Scott, Iain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803554/ https://www.ncbi.nlm.nih.gov/pubmed/35128468 http://dx.doi.org/10.1016/j.crphys.2022.01.005 |
Ejemplares similares
-
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function
por: Thapa, Dharendra, et al.
Publicado: (2020) -
Validation of GCN5L1/BLOC1S1/BLOS1 Antibodies Using Knockout Cells and Tissue
por: Bugga, Paramesha, et al.
Publicado: (2023) -
GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation
por: Thapa, Dharendra, et al.
Publicado: (2022) -
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction
por: Mushala, Bellina A. S., et al.
Publicado: (2023) -
Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway
por: Thapa, Dharendra, et al.
Publicado: (2018)