Cargando…

Bowel perforation due to chronic idiopathic megacolon: Case report and literature review

INTRODUCTION AND IMPORTANCE: Chronic idiopathic megacolon is a rare condition characterized by an irreversible distension of the colon in the absence of organic disease. The pathogenesis of this condition is still unclear and the data in literatures are not consistent. CASE PRESENTATION: We report a...

Descripción completa

Detalles Bibliográficos
Autores principales: Giambusso, Mauro, Fransvea, Pietro, Pepe, Gilda, Sganga, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803594/
https://www.ncbi.nlm.nih.gov/pubmed/35092923
http://dx.doi.org/10.1016/j.ijscr.2022.106777
_version_ 1784642900386119680
author Giambusso, Mauro
Fransvea, Pietro
Pepe, Gilda
Sganga, Gabriele
author_facet Giambusso, Mauro
Fransvea, Pietro
Pepe, Gilda
Sganga, Gabriele
author_sort Giambusso, Mauro
collection PubMed
description INTRODUCTION AND IMPORTANCE: Chronic idiopathic megacolon is a rare condition characterized by an irreversible distension of the colon in the absence of organic disease. The pathogenesis of this condition is still unclear and the data in literatures are not consistent. CASE PRESENTATION: We report a case of an 87-years-old woman affected by bowel perforation in chronic idiopathic megacolon. The patient underwent an emergency subtotal colectomy with terminal ileostomy. The postoperative was uneventful. At the histopathological examination, no organic cause of megacolon was found, so a diagnosis of idiopathic megacolon was done. CLINICAL DISCUSSION: Idiopathic megacolon is difficult to diagnose due to the lack of specific clinical manifestations and pathological features. If not carefully investigated, can lead to severe complications such as perforation of the dilated bowel and subsequent peritonitis and sepsis, metabolic and electrolyte abnormalities. The protocols for management of IMC remains controversial. To achieve a good long-term outcome, early intervention is recommended. CONCLUSION: Early diagnosis of idiopathic megacolon is needed to perform the best therapeutic strategy and prevent complications, but further studies are needed.
format Online
Article
Text
id pubmed-8803594
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-88035942022-02-04 Bowel perforation due to chronic idiopathic megacolon: Case report and literature review Giambusso, Mauro Fransvea, Pietro Pepe, Gilda Sganga, Gabriele Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Chronic idiopathic megacolon is a rare condition characterized by an irreversible distension of the colon in the absence of organic disease. The pathogenesis of this condition is still unclear and the data in literatures are not consistent. CASE PRESENTATION: We report a case of an 87-years-old woman affected by bowel perforation in chronic idiopathic megacolon. The patient underwent an emergency subtotal colectomy with terminal ileostomy. The postoperative was uneventful. At the histopathological examination, no organic cause of megacolon was found, so a diagnosis of idiopathic megacolon was done. CLINICAL DISCUSSION: Idiopathic megacolon is difficult to diagnose due to the lack of specific clinical manifestations and pathological features. If not carefully investigated, can lead to severe complications such as perforation of the dilated bowel and subsequent peritonitis and sepsis, metabolic and electrolyte abnormalities. The protocols for management of IMC remains controversial. To achieve a good long-term outcome, early intervention is recommended. CONCLUSION: Early diagnosis of idiopathic megacolon is needed to perform the best therapeutic strategy and prevent complications, but further studies are needed. Elsevier 2022-01-17 /pmc/articles/PMC8803594/ /pubmed/35092923 http://dx.doi.org/10.1016/j.ijscr.2022.106777 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Giambusso, Mauro
Fransvea, Pietro
Pepe, Gilda
Sganga, Gabriele
Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title_full Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title_fullStr Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title_full_unstemmed Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title_short Bowel perforation due to chronic idiopathic megacolon: Case report and literature review
title_sort bowel perforation due to chronic idiopathic megacolon: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803594/
https://www.ncbi.nlm.nih.gov/pubmed/35092923
http://dx.doi.org/10.1016/j.ijscr.2022.106777
work_keys_str_mv AT giambussomauro bowelperforationduetochronicidiopathicmegacoloncasereportandliteraturereview
AT fransveapietro bowelperforationduetochronicidiopathicmegacoloncasereportandliteraturereview
AT pepegilda bowelperforationduetochronicidiopathicmegacoloncasereportandliteraturereview
AT sgangagabriele bowelperforationduetochronicidiopathicmegacoloncasereportandliteraturereview