PSD3 downregulation confers protection against fatty liver disease

Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a missing heritability component. Using a candidate gene approach, we identify a locus (rs71519934) at the Pleckstr...

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Detalles Bibliográficos
Autores principales: Mancina, Rosellina M., Sasidharan, Kavitha, Lindblom, Anna, Wei, Ying, Ciociola, Ester, Jamialahmadi, Oveis, Pingitore, Piero, Andréasson, Anne-Christine, Pellegrini, Giovanni, Baselli, Guido, Männistö, Ville, Pihlajamäki, Jussi, Kärjä, Vesa, Grimaudo, Stefania, Marini, Ilaria, Maggioni, Marco, Becattini, Barbara, Tavaglione, Federica, Dix, Carly, Castaldo, Marie, Klein, Stephanie, Perelis, Mark, Pattou, Francois, Thuillier, Dorothée, Raverdy, Violeta, Dongiovanni, Paola, Fracanzani, Anna Ludovica, Stickel, Felix, Hampe, Jochen, Buch, Stephan, Luukkonen, Panu K., Prati, Daniele, Yki-Järvinen, Hannele, Petta, Salvatore, Xing, Chao, Schafmayer, Clemens, Aigner, Elmar, Datz, Christian, Lee, Richard G., Valenti, Luca, Lindén, Daniel, Romeo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803605/
https://www.ncbi.nlm.nih.gov/pubmed/35102341
http://dx.doi.org/10.1038/s42255-021-00518-0

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