Cargando…

Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial–Mesenchymal Transition and Responds to Oxidative Stress

Breast cancer cells that have undergone partial epithelial–mesenchymal transition (EMT) are believed to be more invasive than cells that have completed EMT. To study metabolic reprogramming in different mesenchymal states, we analyzed protein expression following EMT in the breast epithelial cell mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qiong, Karvelsson, Sigurdur Trausti, Kotronoulas, Aristotelis, Gudjonsson, Thorarinn, Halldorsson, Skarphedinn, Rolfsson, Ottar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803663/ https://www.ncbi.nlm.nih.gov/pubmed/34923141 http://dx.doi.org/10.1016/j.mcpro.2021.100185

Ejemplares similares

Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
por: Karvelsson, Sigurdur Trausti, et al.
Publicado: (2021)

EGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT
por: Choudhary, Kumari Sonal, et al.
Publicado: (2016)

Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1)
por: Chen, Qiushi, et al.
Publicado: (2015)

Cancer‐associated fibroblast expression of glutamine fructose‐6‐phosphate aminotransferase 2 (GFPT2) is a prognostic marker in gastric cancer
por: Yang, Shuo, et al.
Publicado: (2023)

UDP‐glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines
por: Wang, Qiong, et al.
Publicado: (2022)

NF-κB upregulates glutamine-fructose-6-phosphate transaminase 2 to promote migration in non-small cell lung cancer
por: Szymura, Szymon J., et al.
Publicado: (2019)

Kynurenine aminotransferase 3/glutamine transaminase L/cysteine conjugate beta-lyase 2 is a major glutamine transaminase in the mouse kidney
por: Yang, Cihan, et al.
Publicado: (2016)

Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia
por: Arason, Ari Jon, et al.
Publicado: (2019)

Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification
por: McGarrity, Sarah, et al.
Publicado: (2018)

Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer’s Disease and Inflammation at the Pre- and Early Stages of Dementia
por: Teitsdottir, Unnur D., et al.
Publicado: (2021)

GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway
por: Kroef, Virginia, et al.
Publicado: (2022)

Roles of GFPT2 Expression Levels on the Prognosis and Tumor Microenvironment of Colon Cancer
por: Ding, Xiaorong, et al.
Publicado: (2022)

Inhibition of PTP1B disrupts cell–cell adhesion and induces anoikis in breast epithelial cells
por: Hilmarsdottir, Bylgja, et al.
Publicado: (2017)

Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients
por: Henriksen, Hanne H., et al.
Publicado: (2023)

GFPT1 deficiency in muscle leads to myasthenia and myopathy in mice
por: Issop, Yasmin, et al.
Publicado: (2018)

Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells
por: Sigmarsdottir, Thora Bjorg, et al.
Publicado: (2021)

Exploratory Investigation of the Plasma Proteome Associated with the Endotheliopathy of Trauma
por: Krocker, Joseph D., et al.
Publicado: (2022)

Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2)
por: Oliveira, Isadora A., et al.
Publicado: (2020)

Diverse myopathological features in the congenital myasthenia syndrome with GFPT1 mutation
por: Jiang, Kaiyan, et al.
Publicado: (2022)

Ion Mobility Derived Collision Cross Sections to Support Metabolomics Applications
por: Paglia, Giuseppe, et al.
Publicado: (2014)

deltaNp63 Has a Role in Maintaining Epithelial Integrity in Airway Epithelium
por: Arason, Ari Jon, et al.
Publicado: (2014)

Congenital myasthenic syndrome caused by a frameshift insertion mutation in GFPT1
por: Szelinger, Szabolcs, et al.
Publicado: (2020)

Understanding the Causes and Implications of Endothelial Metabolic Variation in Cardiovascular Disease through Genome-Scale Metabolic Modeling
por: McGarrity, Sarah, et al.
Publicado: (2016)

Characterisation of a novel cardiac phenotype in patients with GFPT1 or DPAGT1 mutations
por: Lewis, Andrew, et al.
Publicado: (2014)

Mutations in gfpt1 and skiv2l2 Cause Distinct Stage-Specific Defects in Larval Melanocyte Regeneration in Zebrafish
por: Yang, Chao-Tsung, et al.
Publicado: (2007)

High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma
por: Gong, Yitao, et al.
Publicado: (2021)

Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction
por: Farshadyeganeh, Paniz, et al.
Publicado: (2023)

Metabolic Heterogeneity, Plasticity, and Adaptation to “Glutamine Addiction” in Cancer Cells: The Role of Glutaminase and the GTωA [Glutamine Transaminase—ω-Amidase (Glutaminase II)] Pathway
por: Cooper, Arthur J. L., et al.
Publicado: (2023)

Silencing of Glutamine: Fructose-6-Phosphate Aminotransferase Impairs Growth and Development in Sogatella furcifera (Hemiptera: Delphacidae)
por: Wang, Zhao, et al.
Publicado: (2023)

Metabolic Response in Endothelial Cells to Catecholamine Stimulation Associated with Increased Vascular Permeability
por: López García de Lomana, Adrián, et al.
Publicado: (2022)

Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
por: Jones, Nicholas, et al.
Publicado: (2021)

Abnormal decrement on high-frequency repetitive nerve stimulation in congenital myasthenic syndrome with GFPT1 mutations and review of literature
por: An, Ran, et al.
Publicado: (2022)

Chemical Mutagenesis and Fluorescence-Based High-Throughput Screening for Enhanced Accumulation of Carotenoids in a Model Marine Diatom Phaeodactylum tricornutum
por: Yi, Zhiqian, et al.
Publicado: (2018)

The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions
por: Rolfsson, Ottar, et al.
Publicado: (2011)

Combined artificial high-silicate medium and LED illumination promote carotenoid accumulation in the marine diatom Phaeodactylum tricornutum
por: Yi, Zhiqian, et al.
Publicado: (2019)

Primary cilia sense glutamine availability and respond via asparagine synthetase
por: Steidl, Maria Elena, et al.
Publicado: (2023)

Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes
por: Prasad, Pushplata, et al.
Publicado: (2010)

A Rise in Aspartate Transaminase and Alanine Transaminase Associated With Ondansetron Administration in a Pregnant Female
por: Couse, Michael, et al.
Publicado: (2020)

Reduction in sucrose contents by downregulation of fructose-1,6-bisphosphatase 2 causes tiller outgrowth cessation in rice mutants lacking glutamine synthetase1;2
por: Ohashi, Miwa, et al.
Publicado: (2018)

Dry-milled flour rice ‘Seolgaeng’ harbors a mutated fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase2
por: Kang, Ju-Won, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_80thh7o0slk3ssn0531ctdba0s