Hybrid total-body pet scanners—current status and future perspectives

Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of conte...

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Autores principales: Nadig, Vanessa, Herrmann, Ken, Mottaghy, Felix M., Schulz, Volkmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803785/
https://www.ncbi.nlm.nih.gov/pubmed/34647154
http://dx.doi.org/10.1007/s00259-021-05536-4
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author Nadig, Vanessa
Herrmann, Ken
Mottaghy, Felix M.
Schulz, Volkmar
author_facet Nadig, Vanessa
Herrmann, Ken
Mottaghy, Felix M.
Schulz, Volkmar
author_sort Nadig, Vanessa
collection PubMed
description Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of contemporary total-body (TB) PET/CT scanners and give an outlook on possible future developments. Results Currently, three human TB PET/CT systems have been developed: The PennPET Explorer, the uExplorer, and the Biograph Vision Quadra realize aFOVs between 1 and 2 m and show a tremendous increase in system sensitivity related to their longer gantries. Conclusion The increased system sensitivity paves the way for short-term, low-dose, and dynamic TB imaging as well as new examination methods in almost all areas of imaging.
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spelling pubmed-88037852022-02-02 Hybrid total-body pet scanners—current status and future perspectives Nadig, Vanessa Herrmann, Ken Mottaghy, Felix M. Schulz, Volkmar Eur J Nucl Med Mol Imaging Review Article Purpose Since the 1990s, PET has been successfully combined with MR or CT systems. In the past years, especially PET systems have seen a trend towards an enlarged axial field of view (FOV), up to a factor of ten. Methods Conducting a thorough literature research, we summarize the status quo of contemporary total-body (TB) PET/CT scanners and give an outlook on possible future developments. Results Currently, three human TB PET/CT systems have been developed: The PennPET Explorer, the uExplorer, and the Biograph Vision Quadra realize aFOVs between 1 and 2 m and show a tremendous increase in system sensitivity related to their longer gantries. Conclusion The increased system sensitivity paves the way for short-term, low-dose, and dynamic TB imaging as well as new examination methods in almost all areas of imaging. Springer Berlin Heidelberg 2021-10-14 2022 /pmc/articles/PMC8803785/ /pubmed/34647154 http://dx.doi.org/10.1007/s00259-021-05536-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Nadig, Vanessa
Herrmann, Ken
Mottaghy, Felix M.
Schulz, Volkmar
Hybrid total-body pet scanners—current status and future perspectives
title Hybrid total-body pet scanners—current status and future perspectives
title_full Hybrid total-body pet scanners—current status and future perspectives
title_fullStr Hybrid total-body pet scanners—current status and future perspectives
title_full_unstemmed Hybrid total-body pet scanners—current status and future perspectives
title_short Hybrid total-body pet scanners—current status and future perspectives
title_sort hybrid total-body pet scanners—current status and future perspectives
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803785/
https://www.ncbi.nlm.nih.gov/pubmed/34647154
http://dx.doi.org/10.1007/s00259-021-05536-4
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