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A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells

T cell activation initiates protective adaptive immunity, but counterbalancing mechanisms are critical to prevent overshooting responses and to maintain immune homeostasis. The CARD11-BCL10-MALT1 (CBM) complex bridges T cell receptor engagement to NF-κB signaling and MALT1 protease activation. Here,...

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Detalles Bibliográficos
Autores principales: Yin, Hongli, Karayel, Ozge, Chao, Ying-Yin, Seeholzer, Thomas, Hamp, Isabel, Plettenburg, Oliver, Gehring, Torben, Zielinski, Christina, Mann, Matthias, Krappmann, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803816/
https://www.ncbi.nlm.nih.gov/pubmed/35099607
http://dx.doi.org/10.1007/s00018-022-04154-z