Cargando…
A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells
T cell activation initiates protective adaptive immunity, but counterbalancing mechanisms are critical to prevent overshooting responses and to maintain immune homeostasis. The CARD11-BCL10-MALT1 (CBM) complex bridges T cell receptor engagement to NF-κB signaling and MALT1 protease activation. Here,...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803816/ https://www.ncbi.nlm.nih.gov/pubmed/35099607 http://dx.doi.org/10.1007/s00018-022-04154-z |