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Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression
The innate immune system represents a balanced first line of defense against infection. Type I interferons (IFNs) are key regulators of the response to viral infections with an essential early wave of IFN-β expression, which is conditional, time-restricted, and stochastic in its nature. The possibil...
Autores principales: | Thomsen, Emil Aagaard, Andersen, Sofie, Marqvorsen, Mikkel Haarslev Schröder, Skipper, Kristian Alsbjerg, Paludan, Søren R., Mikkelsen, Jacob Giehm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803904/ https://www.ncbi.nlm.nih.gov/pubmed/35118008 http://dx.doi.org/10.3389/fcimb.2021.784762 |
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