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Initial evaluation of [(18)F]-FACBC for PET imaging of multiple myeloma

RATIONALE: Multiple myeloma (MM) cells synthesize large amounts of paraproteins, making radiolabeled amino acids promising candidates for PET imaging of MM patients. METHODS: We compare tumor uptake of the two amino acid analogs [(18)F]-fluoroethyltyrosine and [(18)F]-FACBC in a MM xenograft model a...

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Detalles Bibliográficos
Autores principales: Morath, Volker, Heider, Michael, Mittelhäuser, Markus, Rolbieski, Hannes, Stroh, Jacob, Calais, Jérémie, Eiber, Matthias, Bassermann, Florian, Weber, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804025/
https://www.ncbi.nlm.nih.gov/pubmed/35099620
http://dx.doi.org/10.1186/s13550-022-00876-0

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