Cargando…

Hybrid Nanoparticles as a Novel Tool for Regulating Psychosine-Induced Neuroinflammation and Demyelination In Vitro and Ex vivo

Polymeric nanoparticles are being extensively investigated as an approach for brain delivery of drugs, especially for their controlled release and targeting capacity. Nose-to-brain administration of nanoparticles, bypassing the blood brain barrier, offers a promising strategy to deliver drugs to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clementino, Adryana, Velasco-Estevez, Maria, Buttini, Francesca, Sonvico, Fabio, Dev, Kumlesh K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804066/ https://www.ncbi.nlm.nih.gov/pubmed/34480290 http://dx.doi.org/10.1007/s13311-021-01109-3

Ejemplares similares

Design and Characterization of Maltoheptaose-b-Polystyrene Nanoparticles, as a Potential New Nanocarrier for Oral Delivery of Tamoxifen
por: Villetti, Marcos Antonio, et al.
Publicado: (2021)

Olaparib Attenuates Demyelination and Neuroinflammation in an Organotypic Slice Culture Model of Metachromatic Leukodystrophy
por: Mekhaeil, Marianna, et al.
Publicado: (2023)

Surface-Modified Nanocarriers for Nose-to-Brain Delivery: From Bioadhesion to Targeting
por: Sonvico, Fabio, et al.
Publicado: (2018)

Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe’s disease
por: D’Auria, Ludovic, et al.
Publicado: (2017)

In Vitro Evaluation of Curcumin- and Quercetin-Loaded Nanoemulsions for Intranasal Administration: Effect of Surface Charge and Viscosity
por: Vaz, Gustavo, et al.
Publicado: (2022)

Anti-Inflammatory Properties of Statin-Loaded Biodegradable Lecithin/Chitosan Nanoparticles: A Step Toward Nose-to-Brain Treatment of Neurodegenerative Diseases
por: Clementino, Adryana Rocha, et al.
Publicado: (2021)

Structure and Fate of Nanoparticles Designed for the Nasal Delivery of Poorly Soluble Drugs
por: Clementino, Adryana Rocha, et al.
Publicado: (2021)

Preliminary Investigation on Simvastatin-Loaded Polymeric Micelles in View of the Treatment of the Back of the Eye
por: Pescina, Silvia, et al.
Publicado: (2021)

Phospholipase A2 is involved in galactosylsphingosine-induced astrocyte toxicity, neuronal damage and demyelination
por: Misslin, Cedric, et al.
Publicado: (2017)

Inhibition of Cytokinesis by a Lipid Metabolite, Psychosine
por: Kanazawa, Takayuki, et al.
Publicado: (2000)

Psychosine, Cytokinesis, and Orphan Receptors: Unexpected Connections
por: Mitchison, T.J.
Publicado: (2001)

Psychosine variants as antigens for natural killer T cells
por: Deng, S., et al.
Publicado: (2017)

Existing Evidence for the Repurposing of PARP-1 Inhibitors in Rare Demyelinating Diseases
por: Mekhaeil, Marianna, et al.
Publicado: (2022)

Fingolimod Attenuates Splenocyte-Induced Demyelination in Cerebellar Slice Cultures
por: Pritchard, Adam J., et al.
Publicado: (2014)

EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination
por: Rutkowska, Aleksandra, et al.
Publicado: (2017)

Curcumin and Quercetin-Loaded Nanoemulsions: Physicochemical Compatibility Study and Validation of a Simultaneous Quantification Method
por: Vaz, Gustavo Richter, et al.
Publicado: (2020)

The chemokine fractalkine (CX3CL1) attenuates H(2)O(2)-induced demyelination in cerebellar slices
por: O’Sullivan, Sinead A., et al.
Publicado: (2017)

Analysis of age-related changes in psychosine metabolism in the human brain
por: Marshall, Michael S., et al.
Publicado: (2018)

β-Galactosylceramidase in cancer: more than a psychosine scavenger
por: Belleri, Mirella, et al.
Publicado: (2022)

Fingolimod Rescues Demyelination in a Mouse Model of Krabbe's Disease
por: Béchet, Sibylle, et al.
Publicado: (2020)

α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies
por: Abdelkarim, Hazem, et al.
Publicado: (2018)

The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures
por: O’Sullivan, Catherine, et al.
Publicado: (2016)

Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation
por: Im, Dong-Soon, et al.
Publicado: (2001)

Newborn Screening for Krabbe Disease—Illinois Experience: Role of Psychosine in Diagnosis of the Disease
por: Basheeruddin, Khaja, et al.
Publicado: (2021)

Low Psychosine in Krabbe Disease with Onset in Late Infancy: A Case Report
por: Corre, Camille S., et al.
Publicado: (2021)

Tenascins Interfere With Remyelination in an Ex Vivo Cerebellar Explant Model of Demyelination
por: Bauch, Juliane, et al.
Publicado: (2022)

Role of extracellular calcium and mitochondrial oxygen species in psychosine-induced oligodendrocyte cell death
por: Voccoli, V, et al.
Publicado: (2014)

The nasal delivery of nanoencapsulated statins – an approach for brain delivery
por: Clementino, Adryana, et al.
Publicado: (2016)

The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease
por: Reiter, Cory R., et al.
Publicado: (2022)

Recent Patents on Nasal Vaccines Containing Nanoadjuvants
por: Candela, Francesco, et al.
Publicado: (2022)

New ex vivo demyelination/remyelination models to defeat multiple sclerosis and neuromyelitis optica
por: Liu, Yiting
Publicado: (2019)

Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
por: Faucard, Raphaël, et al.
Publicado: (2016)

Inhalable Microparticles Embedding Biocompatible Magnetic Iron-Doped Hydroxyapatite Nanoparticles
por: Quarta, Eride, et al.
Publicado: (2023)

RespiCell(TM): An Innovative Dissolution Apparatus for Inhaled Products
por: Sonvico, Fabio, et al.
Publicado: (2021)

Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow
por: Watanabe, Hiroshi, et al.
Publicado: (2016)

Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in Oligodendrocytes
por: Cheng, An, et al.
Publicado: (2020)

In Vivo Assessment of Clobetasol Propionate-Loaded Lecithin-Chitosan Nanoparticles for Skin Delivery
por: Şenyiğit, Taner, et al.
Publicado: (2016)

Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease
por: Denny, Lisa, et al.
Publicado: (2021)

N,N-dimethylacetamide targets neuroinflammation in Alzheimer’s disease in in-vitro and ex-vivo models
por: Wei, Zeng-Hui, et al.
Publicado: (2023)

EBI2 Is Temporarily Upregulated in MO3.13 Oligodendrocytes during Maturation and Regulates Remyelination in the Organotypic Cerebellar Slice Model
por: Velasco-Estevez, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_21579q343fgfv8h2hu04i2lekg